Syndromic craniosynostosis encompasses an array of diagnoses and genetic mutations that
affect the cranial vault, with additional anomalies in embryologically distinct anatomic sites …

Craniosynostosis results from the premature fusion of cranial sutures, with an incidence of 1
in 2,100-2,500 live births. The majority of cases are non-syndromic and involve single suture …

Background: Fusion of cranial-base sutures/synchondroses presents a clinical conundrum,
given their often unclear “normal” timing of closure. This study investigates the physiologic …

Facial sutures contribute significantly to postnatal facial development, but their potential role
in craniofacial disease is understudied. Since interest in their development and physiology …

Purpose To assess the role of FGFR2 mutations and sutural synostotic patterns on facial
skeleton dysmorphology in children with syndromic craniosynostosis. Methods Preoperative …

Background: Little is known about the detailed growth of the cranial fossae, even though
they provide an important structural connection between the cranial vault and the facial …

Background: Posterior vault distraction osteogenesis (PVDO) has been demonstrated to
effectively increase intracranial volume, treat increased intracranial pressure, and improve …

Purpose The spheno-occipital synchondrosis (SOS) is an important site of endochondral
ossification in the cranial base that closes prematurely in Apert, Crouzon, and Pfeiffer …

Crouzon syndrome patients develop normal intracranial volume and potential restricted
posterior cranial fossa volume with growth. This study aims to trace the segmental anterior …

Background: Spring-mediated cranioplasty (SMC) is an increasingly utilized technique to
treat patients with nonsyndromic sagittal craniosynostosis, but variables impacting outcomes …