Transmission electron microscopy as a powerful tool to investigate the interaction of nanoparticles with subcellular structures

M Malatesta - International Journal of Molecular Sciences, 2021 - mdpi.com
Nanomedical research necessarily involves the study of the interactions between
nanoparticulates and the biological environment. Transmission electron microscopy has …

Colloidal polyelectrolyte complexes from hyaluronic acid: Preparation and biomedical applications

HV Le, D Le Cerf - Small, 2022 - Wiley Online Library
Hyaluronic acid (HA) is a naturally occurring polysaccharide which has been extensively
exploited in biomedical fields owing to its outstanding biocompatibility. Self‐assembly of HA …

Statistical optimization of co-loaded rifampicin and pentamidine polymeric nanoparticles for the treatment of cutaneous leishmaniasis

MM Khan, SS Zaidi, FJ Siyal, SU Khan, G Ishrat… - Journal of Drug Delivery …, 2023 - Elsevier
Topical drug delivery against cutaneous leishmaniasis (CL) serves as an effective alternate
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …

Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Biocompatible hyaluronic acid-divinyl sulfone injectable hydrogels for sustained drug release with enhanced antibacterial properties against Staphylococcus aureus

JA Del Olmo, JM Alonso, VS Martínez… - Materials Science and …, 2021 - Elsevier
Hyaluronic acid (HA) solutions were crosslinked with divinyl sulfone (DVS) and
subsequently loaded with antibiotic molecules to obtain biocompatible and antibacterial …

Drug delivery from hyaluronic Acid–BDDE injectable hydrogels for antibacterial and anti-inflammatory applications

Hyaluronic acid (HA) injectable biomaterials are currently applied in numerous biomedical
areas, beyond their use as dermal fillers. However, bacterial infections and painful …

Hyaluronic acid-based nanomaterials applied to cancer: where are we now?

V Machado, M Morais, R Medeiros - Pharmaceutics, 2022 - mdpi.com
Cancer cells normally develop the ability to rewire or reprogram themselves to become
resistant to treatments that were previously effective. Despite progress in understanding …

Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine: cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate …

M Shariati, G Lollo, K Matha, B Descamps… - … applied materials & …, 2020 - ACS Publications
Intra-abdominal dissemination of peritoneal nodules, a condition known as peritoneal
carcinomatosis (PC), is typically diagnosed in ovarian cancer patients at the advanced …

Nanotechnological approaches for pentamidine delivery

I Andreana, V Bincoletto, P Milla, F Dosio… - Drug Delivery and …, 2022 - Springer
Pentamidine (PTM), which is a diamine that is widely known for its antimicrobial activity, is a
very interesting drug whose mechanism of action is not fully understood. In recent years …

Repurposing pentamidine using hyaluronic acid-based nanocarriers for skeletal muscle treatment in myotonic dystrophy

M Repellin, F Carton, F Boschi, M Galiè… - … , Biology and Medicine, 2023 - Elsevier
In a context of drug repurposing, pentamidine (PTM), an FDA-approved antiparasitic drug,
has been proposed to reverse the splicing defects associated in myotonic dystrophy type 1 …