Neurodegenerative diseases (NDDs) such as Alzheimer's disease, Parkinson's disease and
Huntington's disease (HD), amyotrophic lateral sclerosis, and prion diseases are all …

Diabetic kidney disease is one of the major microvascular complications of both type 1 and
type 2 diabetes mellitus. Approximately 30% of patients with diabetes experience renal …

Axonal degeneration is a common pathological feature in many acute and chronic
neurological diseases such as spinal cord injury (SCI). SARM1 (sterile alpha and TIR motif …

Abstract Protein phosphatase 4 (PP4) plays an indispensable regulatory part in the
development and malignant progression of multifarious tumors. Nevertheless, the function of …

Parkinson's disease (PD) is a common chronic neurodegenerative disease, and the heat
shock proteins (HSPs) are proved to be of great value for PD. In addition, HSPs can maintain …

BIM, a pro-apoptotic BH3-only protein, is a key regulator of the intrinsic (or mitochondrial)
apoptosis pathway. Here, we show that BIM induction by endoplasmic reticulum (ER) stress …

The Leishmaniases are a group of parasitic diseases caused by protozoa of the Leishmania
genus affecting both humans and other vertebrates. Leishmania is an intracellular pathogen …

Glucocorticoids (GCs) are important mediators of key cellular events. Herein, we
investigated the effect of adding cortisol to the IVM medium on the acquisition of …

The exposure of cells to low doses of stress induces adaptive survival responses that protect
cells against subsequent exposure to toxic stress. The ability of cells to resist subsequent …

The ongoing COVID-19 pandemic is a clear and present threat to global public health.
Research into how the causative SARS-CoV-2 virus together with its individual constituent …