ABSTRACT Background In the United States, clozapine was first approved for treatment-
resistant schizophrenia and then for suicidality in schizophrenia psychoses. Systematic …

Health care providers increasingly need to be aware of toxic effects of prescribed and illicit
psychoactive drugs (PADs). 1–4 This article reviews the epidemiology, pharmacology …

Objectives: Describe the pathophysiology of tricyclic antidepressant toxicity. Review the
history and physical exam of a patient with tricyclic antidepressant toxicity. Summarize the …

Suicide is one of the leading causes of death today, and among all mental illness, mood
disorders account for one of the main risk factors. It is well known and proven that suicides …

Objective To investigate the patterns and trends of suspected suicides and suicide attempts
involving antipsychotic or sedative-hypnotic medications reported to United States poison …

Sensitive analysis of nine selected antipsychotic drugs is demonstrated by high performance
liquid chromatography coupled with innovative electrochemical detector employing the non …

Cloud-point extraction (CPE) is rarely combined with liquid chromatography coupled to
mass spectrometry (LC–MS) in drug determination due to the matrix effect (ME). However …

Objectives To determine the numbers and types of medicines dispensed around the time of
death to people who die by suicide; to compare the medicines recently dispensed and those …

Certain postmortem case constellations require intensive investigation of the pattern of drug
use over a long period before death. Hair analysis of illicit drugs has been investigated …

Objetivo. Descrever o perfil toxicológico de todas as vítimas de suicídio no Rio Grande do
Sul, Brasil, de 2017 a 2019. Métodos. Neste estudo descritivo e transversal, foram …