Cell primitive-based biomimetic functional materials for enhanced cancer therapy

GF Luo, WH Chen, X Zeng, XZ Zhang - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell primitive-based functional materials that combine the advantages of natural substances
and nanotechnology have emerged as attractive therapeutic agents for cancer therapy. Cell …

Cause and consequence of heterogeneity in human mesenchymal stem cells: challenges in clinical application

Z Lyu, M Xin, DR Oyston, T Xue, H Kang… - … -Research and Practice, 2024 - Elsevier
Human mesenchymal stem cells (hMSCs) are mesoderm-derived adult stem cells with self-
proliferation capacity, pluripotent differentiation potency, and excellent histocompatibility …

Cell-based nanoparticles delivery systems for targeted cancer therapy: lessons from anti-angiogenesis treatments

P de la Torre, MJ Pérez-Lorenzo, Á Alcázar-Garrido… - Molecules, 2020 - mdpi.com
The main strategy of cancer treatment has focused on attacking the tumor cells. Some
cancers initially responsive to chemotherapy become treatment-resistant. Another strategy is …

Combination of nanomaterials in cell-based drug delivery systems for cancer treatment

L Tang, S He, Y Yin, H Liu, J Hu, J Cheng, W Wang - Pharmaceutics, 2021 - mdpi.com
Cell-based drug delivery systems have shown tremendous advantages in cancer treatment
due to their distinctive properties. For instance, delivery of therapeutics using tumor-tropic …

Anti-cancer immune responses to DNA damage response inhibitors: Molecular mechanisms and progress toward clinical translation

L Carlsen, WS El-Deiry - Frontiers in Oncology, 2022 - frontiersin.org
DNA damage response inhibitors are widely used anti-cancer agents that have potent
activity against tumor cells with deficiencies in various DNA damage response proteins such …

Site-Specific Integration of TRAIL in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy

Z Wang, H Chen, P Wang, M Zhou, G Li… - Stem Cells …, 2022 - academic.oup.com
Mesenchymal stem cells (MSCs) are a promising cellular vehicle for transferring anti-cancer
factors to malignant tumors. Currently, a variety of anti-cancer agents, including the tumor …

[HTML][HTML] Applications of Modified Mesenchymal Stem Cells as Targeted Systems against Tumor Cells

EN Garza Treviño, AG Quiroz Reyes… - International Journal of …, 2024 - mdpi.com
Combined gene and cell therapy are promising strategies for cancer treatment. Given the
complexity of cancer, several approaches are actively studied to fight this disease. Using …

[HTML][HTML] Clinical applications of mesenchymal stromal cell-based therapies for pulmonary diseases: An Update and Concise Review

X Chen, F Wang, Z Huang, Y Wu, J Geng… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Lung disorders are a leading cause of morbidity and death worldwide. For many disease
conditions, no effective and curative treatment options are available. Mesenchymal stromal …

[HTML][HTML] The role of TRAIL signaling in cancer: searching for new therapeutic strategies

C Luo, S He, F Shi, J Zhou, L Shang - Biology, 2024 - mdpi.com
Simple Summary In the realm of modern medicine, the battle against cancer is a relentless
pursuit that demands continuous innovation. Among the numerous elements in the complex …

Targeting of CD133+ cancer stem cells by mesenchymal stem cell expressing TRAIL reveals a prospective role of apoptotic gene regulation in non-small cell lung …

K Shaik Fakiruddin, MN Lim, N Nordin, R Rosli… - Cancers, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy;
however, investigation on its efficacy to target a specific cancer stem cell (CSC) population …