miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review

MT Di Martino, M Arbitrio, D Caracciolo… - … Therapy-Nucleic Acids, 2022 - cell.com
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …

Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1

S Patwardhan, P Mahadik, O Shetty, S Sen - Biomaterials, 2021 - Elsevier
Breast cancer progression features ECM stiffening due to excess deposition and
crosslinking of collagen, which dramatically influence tumor behaviour and fate. The …

Serum exosome-derived piRNAs could be promising biomarkers for HCC diagnosis

T Rui, K Wang, A Xiang, J Guo, N Tang… - International Journal …, 2023 - Taylor & Francis
Background Serum exosome-based liquid biopsy has significant advantages for screening
and diagnosing hepatocellular carcinoma (HCC). P-element-induced wimpy testis (PIWI) …

Advances in therapeutic applications of extracellular vesicles

Y Zhang, Y Dou, Y Liu, M Di, H Bian… - International Journal of …, 2023 - Taylor & Francis
Extracellular vesicles (EVs) are nanoscale bilayer phospholipid membrane vesicles
released by cells. Contained large molecules such as nucleic acid, protein, and lipid, EVs …

Liver fibrosis: Extracellular vesicles mediated intercellular communication in perisinusoidal space

E Devaraj, E Perumal, R Subramaniyan… - …, 2022 - Wiley Online Library
Liver disease is responsible for approximately 1.2 million global deaths per year, which
account for 3.5% of all deaths worldwide.[1] Acute liver injury is often reversible, while …

Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway

B Zhao, J Li, X Zhang, Y Dai, N Yang, Z Bao… - International Journal of …, 2022 - Elsevier
Exosomal miRNAs are verified critical biomarkers, which participate in several biological
processes. The growth and development of the hair follicle (HF) are typically controlled by …

Selenium and nitrogen co-doped carbon dots with highly efficient electrochemiluminescence for ultrasensitive detection of microRNA

J Liu, J Chen, Y Zhang, L Liu, YZ Guo, R Yuan… - Biosensors and …, 2023 - Elsevier
In this work, selenium and nitrogen co-doped carbon dots (SeN-CDs) possessing highly
efficient electrochemiluminescence (ECL) and excellent biocompatibility were synthesized …

Small non-coding RNAs in human cancer

Q Xiong, Y Zhang, J Li, Q Zhu - Genes, 2022 - mdpi.com
Small non-coding RNAs are widespread in the biological world and have been extensively
explored over the past decades. Their fundamental roles in human health and disease are …

Clinical applications of liquid biopsy in hepatocellular carcinoma

JC Yang, JJ Hu, YX Li, W Luo, JZ Liu, DW Ye - Frontiers in Oncology, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common malignant tumor with high mortality and poor
prognosis in the world. The low rate of early diagnosis, as well as the high risk of …