Discovery and mechanism-guided engineering of BHET hydrolases for improved PET recycling and upcycling

A Li, Y Sheng, H Cui, M Wang, L Wu, Y Song… - Nature …, 2023 - nature.com
Although considerable research achievements have been made to address the plastic crisis
using enzymes, their applications are limited due to incomplete degradation and low …

[HTML][HTML] Degradation of polymer materials in the environment and its impact on the health of experimental animals: a review

X Zhang, Z Yin, S Xiang, H Yan, H Tian - Polymers, 2024 - pmc.ncbi.nlm.nih.gov
The extensive use of polymeric materials has resulted in significant environmental pollution,
prompting the need for a deeper understanding of their degradation processes and impacts …

Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading

Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li… - Nature …, 2024 - nature.com
Biotechnological plastic recycling has emerged as a suitable option for addressing the
pollution crisis. A major breakthrough in the biodegradation of poly (ethylene …

Computational design of highly efficient thermostable MHET hydrolases and dual enzyme system for PET recycling

J Zhang, H Wang, Z Luo, Z Yang, Z Zhang… - Communications …, 2023 - nature.com
Recently developed enzymes for the depolymerization of polyethylene terephthalate (PET)
such as FAST-PETase and LCC-ICCG are inhibited by the intermediate PET product mono …

Chemical recycling of polyester textile wastes: shifting towards sustainability

T El Darai, A Ter-Halle, M Blanzat, G Despras… - Green …, 2024 - pubs.rsc.org
Amongst all synthetic polymers used in the clothing industry, polyethylene terephthalate
(PET) is the most widely used polyester, its fibres representing half the total PET global …

[HTML][HTML] A novel Bacillus subtilis BPM12 with high bis (2 hydroxyethyl) terephthalate hydrolytic activity efficiently interacts with virgin and mechanically recycled …

B Pantelic, JA Araujo, S Jeremic, M Azeem… - … Technology & Innovation, 2023 - Elsevier
Biotechnological treatment of plastic waste has gathered substantial attention as an efficient
and generally greener approach for polyethylene terephthalate (PET) depolymerization and …

Rational mutagenesis of Thermobifida fusca cutinase to modulate the enzymatic degradation of polyethylene terephthalate

A Mrigwani, M Pitaliya, H Kaur… - Biotechnology and …, 2023 - Wiley Online Library
Thermobifida fusca cutinase (TfCut2) is a carboxylesterase (CE) which degrades
polyethylene terephthalate (PET) as well as its degradation intermediates [such as …

Engineering dual-functional and thermophilic BMHETase for efficient degradation of polyethylene terephthalate

R Miao, G Xu, Y Ding, Z Ding, J Woodard, T Tu… - Bioresource …, 2024 - Elsevier
Polyethylene terephthalate (PET) biodegradation is hindered by the intermediates bis (2-
hydroxyethyl) terephthalate (BHET) and mono (2-hydroxyethyl) terephthalate (MHET) …

The evolution of cutinase Est1 based on the clustering strategy and its application for commercial PET bottles degradation

D Lu, Y Chen, S Jin, Q Wu, J Wu, J Liu, F Wang… - Journal of …, 2024 - Elsevier
The rapid increase in global plastic consumption, especially the worldwide use of
polyethylene terephthalate (PET), has caused serious pollution problems. Due to the low …

Counter‐intuitive enhancement of degradation of polyethylene terephthalate through engineering of lowered enzyme binding to solid plastic

A Mrigwani, B Thakur… - … : Structure, Function, and …, 2023 - Wiley Online Library
Degradation of solid polyethylene terephthalate (PET) by leaf branch compost cutinase
(LCC) produces various PET‐derived degradation intermediates (DIs), in addition to …