Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Tailoring materials for epilepsy imaging: from biomarkers to imaging probes

J Zhao, C Wang, W Sun, C Li - Advanced Materials, 2022 - Wiley Online Library
Excising epileptic foci (EF) is the most efficient approach for treating drug‐resistant epilepsy
(DRE). However, owing to the vast heterogeneity of epilepsies, EF in one‐third of patients …

Adenosine receptors and epilepsy: current evidence and future potential

SA Masino, M Kawamura Jr, DN Ruskin - International review of …, 2014 - Elsevier
Adenosine receptors are a powerful therapeutic target for regulating epileptic seizures. As a
homeostatic bioenergetic network regulator, adenosine is perfectly suited to establish or …

Corticohippocampal circuit dysfunction in a mouse model of Dravet syndrome

J Mattis, A Somarowthu, KM Goff, E Jiang, J Yom… - Elife, 2022 - elifesciences.org
Dravet syndrome (DS) is a neurodevelopmental disorder due to pathogenic variants in
SCN1A encoding the Nav1. 1 sodium channel subunit, characterized by treatment-resistant …

Unaltered network activity and interneuronal firing during spontaneous cortical dynamics in vivo in a mouse model of severe myoclonic epilepsy of infancy

AM De Stasi, P Farisello, I Marcon, S Cavallari… - Cerebral …, 2016 - academic.oup.com
Severe myoclonic epilepsy of infancy (SMEI) is associated with loss of function of the
SCN1A gene encoding the NaV1. 1 sodium channel isoform. Previous studies in Scn1a−/+ …

Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during …

MS Tsai, ML Lee, CY Chang, HH Fan, IS Yu… - Neurobiology of …, 2015 - Elsevier
Dravet syndrome (DS) is characterized by severe infant-onset myoclonic epilepsy along with
delayed psychomotor development and heightened premature mortality. A primary …

The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization

N Hübel, MS Hosseini-Zare, J Žiburkus… - PLoS computational …, 2017 - journals.plos.org
Simultaneous changes in ion concentrations, glutamate, and cell volume together with
exchange of matter between cell network and vasculature are ubiquitous in numerous brain …

Genetic and molecular basis of epilepsy-related cognitive dysfunction

L Zhu, L Chen, P Xu, D Lu, S Dai, L Zhong, Y Han… - Epilepsy & Behavior, 2020 - Elsevier
Epilepsy is a common neurological disease characterized by recurrent seizures. About 70
million people were affected by epilepsy or epileptic seizures. Epilepsy is a complicated …

From molecular circuit dysfunction to disease: case studies in epilepsy, traumatic brain injury, and Alzheimer's disease

CG Dulla, DA Coulter, J Ziburkus - The Neuroscientist, 2016 - journals.sagepub.com
Complex circuitry with feed-forward and feed-back systems regulate neuronal activity
throughout the brain. Cell biological, electrical, and neurotransmitter systems enable neural …

Effects of experimental traumatic brain injury and impaired glutamate transport on cortical spreading depression

MS Hosseini-Zare, F Gu, A Abdulla, S Powell… - Experimental …, 2017 - Elsevier
Cortical spreading depression (CSD) is associated with traumatic brain injury (TBI), stroke,
migraines, and seizures. Typically, following TBIs and other insults, neuronal excitability in …