The spread of Plasmodium falciparum isolates carrying mutations in the kelch13 (Pfkelch13)
gene associated with artemisinin resistance (PfART-R) in southeast Asia threatens malaria …

Malaria affects 200 million people worldwide. Today, the most successful treatments are
artemisinin-based combination therapies (ACT). Resistance has already been described for …

Antimalarial drug resistance is a major global challenge in malaria control and elimination.
Mutations in six different genes of Plasmodium falciparum (crt, mdr1, dhfr, dhps, ATPase6 …

Background The devastating public health impact of malaria has prompted the need for
effective interventions. Malaria control gained traction after the introduction of artemisinin …

The effectiveness of artemisinin-based combination therapies (ACTs) depends not only on
that of artemisinin but also on that of partner molecules. This study aims to evaluate the …

Since the 2007 French guidelines on imported Falciparum malaria, the epidemiology,
treatment, and prevention of malaria have changed considerably requiring guidelines for all …

The objective of this study was to analyze the relationship between the frequency of
artemisinin-based combination (ACT) drug resistance molecular markers and clinical forms …

This study aimed to analyze polymorphisms in Pfcrt, Pfmdr1, and Pfk13 genes' markers of
resistance to Artemisinin-based combination therapy (ACT), in Plasmodium falciparum …

Background Malaria remains a major public health problem, affecting mainly low-and middle-
income countries. The management of this parasitic disease is challenged by ever …

Background Malaria control efforts in Sudan rely heavily on case management. In 2004,
health authorities adopted artemisinin-based combination therapies (ACTs) for the treatment …