[HTML][HTML] Impact of inflammation on ferritin, hepcidin and the management of iron deficiency anemia in chronic kidney disease

N Ueda, K Takasawa - Nutrients, 2018 - mdpi.com
Iron deficiency anemia (IDA) is a major problem in chronic kidney disease (CKD), causing
increased mortality. Ferritin stores iron, representing iron status. Hepcidin binds to …

Sequestration and scavenging of iron in infection

NL Parrow, RE Fleming, MF Minnick - Infection and immunity, 2013 - Am Soc Microbiol
The proliferative capability of many invasive pathogens is limited by the bioavailability of
iron. Pathogens have thus developed strategies to obtain iron from their host organisms. In …

[HTML][HTML] Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model

J Wang, Y Wang, Y Liu, X Cai, X Huang, W Fu… - Cell death …, 2022 - nature.com
Ferroptosis is a non-traditional form of regulated cell death, characterized by iron overload
and lipid peroxidation. Exploration of ferroptosis in chronic kidney disease (CKD) has been …

[HTML][HTML] Macrophage activation marker soluble CD163 associated with fatal and severe Ebola virus disease in humans

AK McElroy, P Shrivastava-Ranjan… - Emerging Infectious …, 2019 - ncbi.nlm.nih.gov
Ebola virus disease (EVD) is associated with elevated cytokine levels, and
hypercytokinemia is more pronounced in fatal cases. This type of hyperinflammatory state is …

[HTML][HTML] Di-(2-ethylhexyl) phthalate exposure induces liver injury by promoting ferroptosis via downregulation of GPX4 in pregnant mice

F Zhang, H Zhen, H Cheng, F Hu, Y Jia… - Frontiers in Cell and …, 2022 - frontiersin.org
As one kind of endocrine disrupting chemical, di-(2-ethylhexyl) phthalate (DEHP) has been
reported to cause liver dysfunction in epidemiological and experimental studies. Abnormal …

The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus

SL Fowler, M Akins, H Zhou, D Figeys… - Journal of proteome …, 2013 - ACS Publications
Connexins are the structural subunits of gap junctions and act as protein platforms for
signaling complexes. Little is known about tissue-specific connexin signaling nexuses, given …

[HTML][HTML] Computational and biological investigation of the soybean lecithin–gallic acid complex for ameliorating alcoholic liver disease in mice with iron overload

X Wu, Y Wang, R Jia, F Fang, Y Liu, W Cui - Food & function, 2019 - pubs.rsc.org
Alcoholic liver disease (ALD) is associated with significant morbidity and mortality globally.
In this study, the soybean lecithin–gallic acid complex was synthesized, and its …

Obesity is associated with gene expression and imaging markers of iron accumulation in skeletal muscle

JM Moreno-Navarrete, G Blasco, G Xifra… - The Journal of …, 2016 - academic.oup.com
Context: Different genetic and imaging iron markers are known to be increased in the liver,
adipose tissue, and brain of obese subjects. Objective: We aimed to investigate these …

[HTML][HTML] Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines

S Khan, S Cameron, M Blaschke… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To study KRAS/BRAF mutations in colorectal-cancer (CRC) that influences the efficacy
of treatment. To develop strategies for overcoming combination of treatment. METHODS …

[HTML][HTML] Hepatic fat accumulation and regulation of FAT/CD36: an effect of hepatic irradiation

G Martius, SM Alwahsh, M Rave-Fränk… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Irradiation is known to induce inflammation and affect fat metabolic pathways. The current
study investigates hepatic fat accumulation and fatty acid transportation in a rat model of …