Normal aging induces changes in the brain and neurodegeneration progress: review of the structural, biochemical, metabolic, cellular, and molecular changes

J Lee, HJ Kim - Frontiers in aging neuroscience, 2022 - frontiersin.org
Aging is accompanied by many changes in brain and contributes to progressive cognitive
decline. In contrast to pathological changes in brain, normal aging brain changes have …

Mechanisms linking obesity and its metabolic comorbidities with cerebral grey and white matter changes

I García-García, A Michaud, MÁ Jurado… - Reviews in Endocrine …, 2022 - Springer
Obesity is a preventable risk factor for cerebrovascular disorders and it is associated with
cerebral grey and white matter changes. Specifically, individuals with obesity show …

Cohort profile: the LIFE-adult-study

C Engel, K Wirkner, S Zeynalova… - International Journal …, 2023 - academic.oup.com
International Journal of Epidemiology, 2023, e66–e79 https://doi. org/10.1093/ije/dyac114
Advance Access Publication Date: 28 May 2022 Cohort Profile comprehensive molecular …

Brain damage with heart failure: cardiac biomarker alterations and gray matter decline

K Mueller, F Thiel, F Beutner, A Teren, S Frisch… - Circulation …, 2020 - Am Heart Assoc
Rationale: Heart failure (HF) following heart damage leads to a decreased blood flow due to
a reduced pump efficiency of the heart muscle. A consequence can be insufficient oxygen …

A functional connectome signature of blood pressure in> 30 000 participants from the UK biobank

R Jiang, VD Calhoun, S Noble, J Sui… - Cardiovascular …, 2023 - academic.oup.com
Aims Elevated blood pressure (BP) is a prevalent modifiable risk factor for cardiovascular
diseases and contributes to cognitive decline in late life. Despite the fact that functional …

Optimal blood pressure keeps our brains younger

N Cherbuin, EI Walsh, M Shaw, E Luders… - Frontiers in Aging …, 2021 - frontiersin.org
Background: Elevated blood pressure (BP) is a major health risk factor and the leading
global cause of premature death. Hypertension is also a risk factor for cognitive decline and …

Higher blood pressure is associated with greater white matter lesions and brain atrophy: a systematic review with meta-analysis

K Alateeq, EI Walsh, N Cherbuin - Journal of clinical medicine, 2021 - mdpi.com
Background: To summarise and quantify the evidence on the association between Blood
pressure (BP), white matter lesions (WMLs), and brain volumes. Method: Electronic …

Neuroanatomical correlates of cognitive impairment following basal ganglia-thalamic post-hemorrhagic stroke: Uncovering network-wide alterations in hemispheric …

H Wang, M Yu, J Ren, X Zhong, D Xu, L Gao, H Xu - Brain Research, 2023 - Elsevier
Cognitive impairment and recovery are central issues in hemorrhagic stroke. This study
aimed to investigate whether post-hemorrhagic stroke cognitive impairment (PhSCI) is …

[HTML][HTML] Obesity is associated with reduced orbitofrontal cortex volume: a coordinate-based meta-analysis

EY Chen, SB Eickhoff, T Giovannetti, DV Smith - NeuroImage: Clinical, 2020 - Elsevier
Neural models of obesity vary in their focus upon prefrontal and striatal differences. Animal
and human studies suggest that differential functioning of the orbitofrontal cortex is …

Decreased gray matter volume in the right middle temporal gyrus associated with cognitive dysfunction in preeclampsia superimposed on chronic hypertension

C Sui, H Wen, J Han, T Chen, Y Gao, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction The effects of preeclampsia superimposed on chronic hypertension (CHTN-PE)
on the structure and function of the human brain are mostly unknown. The purpose of this …