Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Shape‐controlled synthesis of metal nanocrystals: simple chemistry meets complex physics?

Y Xia, Y Xiong, B Lim… - Angewandte Chemie …, 2009 - Wiley Online Library
Nanocrystals are fundamental to modern science and technology. Mastery over the shape of
a nanocrystal enables control of its properties and enhancement of its usefulness for a given …

Biosensing with plasmonic nanosensors

JN Anker, WP Hall, O Lyandres, NC Shah, J Zhao… - Nature materials, 2008 - nature.com
Recent developments have greatly improved the sensitivity of optical sensors based on
metal nanoparticle arrays and single nanoparticles. We introduce the localized surface …

LSPR-based nanobiosensors

B Sepúlveda, PC Angelomé, LM Lechuga… - Nano today, 2009 - Elsevier
Recent progress in nano-optics has paved the route toward the development of highly
sensitive and label-free optical transducers using the localized surface plasmon resonance …

Mass spectrometric imaging for biomedical tissue analysis

K Chughtai, RMA Heeren - Chemical reviews, 2010 - ACS Publications
A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

Imaging mass spectrometry

LA McDonnell, RMA Heeren - Mass spectrometry reviews, 2007 - Wiley Online Library
Imaging mass spectrometry combines the chemical specificity and parallel detection of mass
spectrometry with microscopic imaging capabilities. The ability to simultaneously obtain …

Metabolic fingerprinting as a diagnostic tool

DI Ellis, WB Dunn, JL Griffin, JW Allwood… - …, 2007 - Taylor & Francis
Within the framework of systems biology, functional analyses at all 'omic levels have seen an
intense level of activity during the first decade of the twenty-first century. These include …

Nanoparticle-based mass spectrometry for the analysis of biomolecules

CK Chiang, WT Chen, HT Chang - Chemical Society Reviews, 2011 - pubs.rsc.org
Nanoparticles (NPs) are useful as matrixes for the analyses of several types of biomolecules
(including aminothiols, peptides, and proteins) and for mass spectrometric imaging through …

Clathrate nanostructures for mass spectrometry

TR Northen, O Yanes, MT Northen, D Marrinucci… - Nature, 2007 - nature.com
The ability of mass spectrometry to generate intact biomolecular ions efficiently in the gas
phase has led to its widespread application in metabolomics, proteomics, biological …

Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

HN Abdelhamid - Microchimica Acta, 2019 - Springer
Great endeavors are undertaken to find effective nanoparticles to replace organic matrices
for the analysis of small molecules using laser desorption ionization mass spectrometry (LDI …