The poly-l-proline type II (PPII) helix in recent years has emerged clearly as a structural class
not only of fibrillar proteins (in collagen, PPII is a dominant conformation) but also of the …

The gram-positive bacterium Listeria monocytogenes is the causative agent of listeriosis, a
highly fatal opportunistic foodborne infection. Pregnant women, neonates, the elderly, and …

Wnt signaling through the canonical β-catenin pathway plays essential roles in development
and disease. L ow-density-lipoprotein receptor-r elated p roteins 5 and 6 (Lrp5 and Lrp6) in …

The process by which extracellular signals are relayed from the plasma membrane to
specific intracellular sites is an essential facet of cellular regulation. Many signaling …

Axon outgrowth and guidance to the proper target requires the coordination of filamentous
(F)-actin and microtubules (MTs), the dynamic cytoskeletal polymers that promote shape …

ABSTRACT A common focus among molecular and cellular biologists is the identification of
proteins that interact with each other. Yeast two‐hybrid, cDNA expression library screening …

We have found that epithelial cells engage in a process of cadherin-mediated intercellular
adhesion that utilizes calcium and actin polymerization in unexpected ways. Calcium …

The robo gene in Drosophila was identified in a large-scale mutant screen for genes that
control the decision by axons to cross the CNS midline. In robo mutants, too many axons …

Completely revised, this third edition of a bestseller incorporates findings to present readers
with a complete overview of foodborne listeriosis, including information on listeriosis in …

Cell motility requires lamellipodial protrusion, a process driven by actin polymerization.
Ena/VASP proteins accumulate in protruding lamellipodia and promote the rapid actin …