Short-chain fatty acids in cancer pathogenesis

MA Feitelson, A Arzumanyan, A Medhat… - Cancer and Metastasis …, 2023 - Springer
Cancer is a multi-step process that can be viewed as a cellular and immunological shift
away from homeostasis in response to selected infectious agents, mutations, diet, and …

Biochemical and metabolical pathways associated with microbiota-derived butyrate in colorectal cancer and omega-3 fatty acids implications: A narrative review

AS Gheorghe, ȘM Negru, M Preda, RI Mihăilă… - Nutrients, 2022 - mdpi.com
Knowledge regarding the influence of the microbial community in cancer promotion or
protection has expanded even more through the study of bacterial metabolic products and …

Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

S Bettini, E Boutet-Robinet, C Cartier, C Coméra… - Scientific reports, 2017 - nature.com
Food-grade titanium dioxide (TiO2) containing a nanoscale particle fraction (TiO2-NPs) is
approved as a white pigment (E171 in Europe) in common foodstuffs, including …

Dietary fiber treatment corrects the composition of gut microbiota, promotes SCFA production, and suppresses colon carcinogenesis

F Bishehsari, PA Engen, NZ Preite, YE Tuncil, A Naqib… - Genes, 2018 - mdpi.com
Epidemiological studies propose a protective role for dietary fiber in colon cancer (CRC).
One possible mechanism of fiber is its fermentation property in the gut and ability to change …

Fermentation of fructooligosaccharides and inulin by bifidobacteria: a comparative study of pure and fecal cultures

M Rossi, C Corradini, A Amaretti… - Applied and …, 2005 - Am Soc Microbiol
The utilization of fructooligosaccharides (FOS) and inulin by 55 Bifidobacterium strains was
investigated. Whereas FOS were fermented by most strains, only eight grew when inulin was …

In vitro fermentation and prebiotic potential of novel low molecular weight polysaccharides derived from agar and alginate seaweeds

P Ramnani, R Chitarrari, K Tuohy, J Grant, S Hotchkiss… - Anaerobe, 2012 - Elsevier
Fermentation properties and prebiotic potential of novel low molecular weight
polysaccharides (LMWPs) derived from agar and alginate bearing seaweeds was …

Dietary polyunsaturated fatty acids and heme iron induce oxidative stress biomarkers and a cancer promoting environment in the colon of rats

F Guéraud, S Taché, JP Steghens, L Milkovic… - Free Radical Biology …, 2015 - Elsevier
The end products of polyunsaturated fatty acid (PUFA) peroxidation, such as
malondialdehyde (MDA), 4-hydroxynonenal (HNE), and isoprostanes (8-iso-PGF 2α), are …

In vitro comparison of the prebiotic effects of two inulin-type fructans

A Pompei, L Cordisco, S Raimondi, A Amaretti… - Anaerobe, 2008 - Elsevier
Faecal cultures were used to compare the prebiotic effects of a new fructan containing high
solubility inulin (HSI) and of a well-established prebiotic containing oligofructose (OF) with a …

[HTML][HTML] Adenomatous Polyposis Coli (APC) in cell migration

X Fang, TM Svitkina - European journal of cell biology, 2022 - Elsevier
Abstract Adenomatous Polyposis Coli (APC) protein is mostly known as a tumor suppressor
that regulates Wnt signaling, but is also an important cytoskeletal protein. Mutations in the …

[HTML][HTML] Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human …

FHF Pierre, OCB Martin, RL Santarelli, S Taché… - The American journal of …, 2013 - Elsevier
Background: Processed meat intake has been associated with increased colorectal cancer
risk. We have shown that cured meat promotes carcinogen-induced preneoplastic lesions …