The possible link between hIAPP accumulation and β-cell death in diabetic patients has
inspired numerous studies focusing on amyloid structures and aggregation pathways of this …

Limonene is a monoterpene confined to the family of Rutaceae, showing several biological
properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and …

Covering: 2015 up to 2022 (Feb) Silymarin, an extract of milk thistle (Silybum marianum)
fruits, has been used in various medicinal applications since ancient times. A major …

Phytochemicals are known to have anti-inflammatory effects in vitro and in vivo, such as in
inflammatory disease model systems. Inflammation is an essential immune response to …

Bisphenol A (BPA), a well-known xenoestrogen, is commonly utilised in the production of
polycarbonate plastics. Based on the existing evidence, BPA is known to induce …

Silymarin is an extract from the seeds (fruits) of Silybum marianum that contains
flavonolignans and flavonoids. Although it is frequently used as a hepatoprotective agent, its …

Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common
products widely used in the phytotherapy of liver diseases. They also have promising effects …

Accumulation of amyloid-β (Aβ), which results in the formation of senile plaques that cause
oxidative damage and neuronal cell death, has been accepted as the major pathological …

Covering: 2012 to 2023 The human population is aging. Thus, the greatest risk factor for
numerous diseases, such as diabetes, cancer and neurodegenerative disorders, is …

This review focuses on the specific biological effects of optically pure silymarin flavo-
nolignans, mainly silybins A and B, isosilybins A and B, silychristins A and B, and their 2, 3 …