Tuberculous meningitis (TBM) is the most devastating form of tuberculosis (TB), causing
high mortality or disability. Clinical management of the disease is challenging due to …

Tuberculosis (TB) is one of the main infectious diseases worldwide and accounts for many
deaths. It is caused by Mycobacterium tuberculosis usually affecting the lungs of patients …

Improved tuberculosis diagnostics and tools for monitoring treatment response are urgently
needed. We developed a robust and simple, PCR-based host-blood transcriptomic …

Importance Latent tuberculosis infection (LTBI) can progress to active tuberculosis disease,
causing morbidity and mortality. Objective To review the evidence on benefits and harms of …

More humans have died of tuberculosis (TB) than any other infectious disease and millions
still die each year. Experts advocate for blood-based, serum protein biomarkers to help …

Background Multiple host blood transcriptional signatures have been developed as non-
sputum triage tests for tuberculosis (TB). We aimed to compare the diagnostic performance …

Accurate and affordable point-of-care diagnostics for tuberculosis (TB) are needed. Host
serum protein signatures have been derived for use in primary care settings, however …

Tuberculosis (TB) remains a major global threat and diagnosis of active TB ((ATB) both extra-
pulmonary (EPTB), pulmonary (PTB)) and latent TB (LTBI) infection remains challenging …

Objective To investigate the potential of host urinary biomarkers as diagnostic candidates for
tuberculosis (TB). Methods Adults self-presenting with symptoms requiring further …

Tuberculosis (TB) is defined as a chronic infection in both human and cattle hosts and many
subclinical cases remain undetected. After the pathogen is inhaled by a host, phagocyted …