Lampaya Medicinalis Phil. decreases lipid-induced triglyceride accumulation and proinflammatory markers in human hepatocytes and fat body of Drosophila …

S Sanhueza, N Tobar, M Cifuentes, D Quenti… - International Journal of …, 2021 - nature.com
Background Excess hepatic triglyceride (TG) accumulation (steatosis) commonly observed
in obesity, may lead to non-alcoholic fatty liver disease (NAFLD). Altered regulation of …

Effect of Lampaya medicinalis Phil. (Verbenaceae) and Palmitic Acid on Insulin Signaling and Inflammatory Marker Expression in Human Adipocytes

G Yuri, M Cifuentes, P Cisternas, A Paredes… - Pharmaceuticals, 2024 - mdpi.com
Background: Aging and obesity are associated with insulin resistance (IR) and low-grade
inflammation. Molecularly, IR is characterized by a reduction in glucose uptake and insulin …

Anti-inflammatory activity of Mollugo cerviana methanolic extract in LPS-induced acute inflammatory RAW 264.7 macrophages

R Antony, J Raveendran, PG Biju - Combinatorial Chemistry & …, 2022 - ingentaconnect.com
Background: The management of acute inflammation, which arises from complex biological
responses to harmful stimuli, is an important determinant in the recovery from an otherwise …

Protective effect of the hydroalcoholic extract from Lampaya medicinalis Phil.(Verbenaceae) on palmitic acid-impaired insulin signaling in 3T3-L1 adipocytes

P Ormazabal, K Herrera, M Cifuentes, A Paredes… - Obesity Research & …, 2020 - Elsevier
Background Obesity is strongly associated with insulin resistance (IR). IR at the molecular
level may be defined as a diminished activation of insulin signaling-related molecules (IRS …

Deleterious liver-adipose crosstalk in obesity: Hydroethanolic extract of Lampaya medicinalis Phil.(Verbenaceae) counteracts fatty acid-induced fibrotic marker …

G Yuri, S Sanhueza, A Paredes, G Morales… - Molecular and Cellular …, 2023 - Elsevier
Elevated circulating fatty acids in obesity may induce hepatic steatosis, leading to liver
inflammation, fibrosis and nonalcoholic fatty liver disease (NAFLD). On the other hand …

[HTML][HTML] Antiplatelet activity of Lampaya medicinalis Phil. in human platelets

P Ormazabal, L Rodriguez, A Paredes, G Morales… - NFS Journal, 2022 - Elsevier
Herbal preparations can have beneficial effects to counteract cardiovascular diseases
(CVD). Inhibition of platelet aggregation have been shown to be effective in CVD treatment …

[HTML][HTML] Efecto del extracto hidroalcohólico de la planta Lampaya medicinalis Phil.(Verbenaceae) sobre la esteatosis inducida in vitro en hepatocitos humanos

P Ormazábal, G Yuri, S Sanhueza… - Rev. chil …, 2021 - pesquisa.bvsalud.org
OBJETIVO: Evaluar el efecto de un extracto hidroalcóholico de lampaya (EHL) sobre la
esteatosis y expresión de marcadores de inflamación en hepatocitos tratados con ácidos …

[HTML][HTML] Efecto del extracto hidroalcohólico de la planta Lampaya medicinalis Phil. sobre marcadores inflamación inducidos por ácidos grasos en hepatocitos …

P Ormazabal, G Yuri, S Sanhueza… - Revista chilena de …, 2022 - SciELO Chile
Introducción: la enfermedad de hígado graso no alcohólico (EHGNA) se caracteriza por la
acumulación de gotas lipídicas (GL) y sobre expresión de la proteína de GL Perilipina 1 …

Adipocyte ZAG improves obesity-triggered insulin resistance by reshapingmacrophages populations in adipose tissue

L Ran, C Hu, T Peng, L Wu, Y Wang, J Yang - 2023 - researchsquare.com
Adipose tissues macrophages (ATMs) serve as a critical effector in the mediating occurrence
of metabolic inflammation to impact whole-body insulin sensitivity in obesity. Discovering the …

[PDF][PDF] Reunión Clínica 4 de julio 2020

MPVSLAA DE, LYLAE DE MARCADORES… - soched.cl
Introducción: La enfermedad del hígado graso no alcohólico (EHGNA) es una patología
asociada a la obesidad que se caracteriza por una acumulación anormal de triglicéridos …