Cystic fibrosis (CF) is a life-shortening autosomal recessive disorder caused by mutations in
the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR …

Cystic fibrosis is a complex multi-systemic chronic disease characterized by progressive
organ dysfunction with development of fibrosis, possibly affecting the heart. Over the last four …

Cystic fibrosis (CF) is a genetic, multisystemic disorder with broad clinical manifestations
apart from the well-characterized pulmonary dysfunction. Recent findings have described …

Background and objective: Over 2000 genotypes in the cystic fibrosis (CF) gene have been
described. These genotypic differences result in variable clinical manifestations of CF, with …

The understanding of binding interactions between any protein and a small molecule plays
a key role in the rationalization of affinity and selectivity. It is essential for an efficient …

Background The pathophysiological roles of cystic fibrosis transmembrane-conductance
regulator (CFTR) Cl− channels in the regulation of blood pressure (BP) remain controversial …

目的探讨强制性运动疗法对急性脑卒中后偏瘫患者早期神经功能的影响. 方法选取于2011 年8
月-2014 年2 月在首都医科大学北京朝阳医院, 北京英智康复医院进行诊治的急性脑卒中后偏瘫 …

Background: Cystic fibrosis (CF) is a genetic disease affecting multiple organ systems of the
body and is characterized by mutation in the gene coding for the cystic fibrosis …

Background Individuals with cystic fibrosis (CF) have reduced pulmonary function and
exercise tolerance. Additionally, these individuals may develop abnormal cardiac function …

Purpose Cystic fibrosis (CF) is commonly recognized as a pulmonary disease associated
with reduced airway function. Another primary symptom of CF is low exercise capacity where …