Advances in our understanding of molecular mechanisms of tumorigenesis have translated
into knowledge-based therapies directed against specific oncogenic signaling targets …

Breast cancer is a complex and heterogeneous disease. Gene expression profiling has
contributed significantly to our understanding of this heterogeneity at a molecular level …

The mechanisms behind cancer initiation and progression are not clear. Therefore,
development of clinically relevant models to study cancer biology and drug response in …

The causes of metastasis remain elusive despite vast information on cancer cells. We posit
that cancer cell fusion with macrophages or other migratory bone marrow-derived cells …

Primary aldosteronism is the most common single cause of hypertension and is potentially
curable when only one adrenal gland is the culprit. The importance of primary aldosteronism …

Tumor blood vessels are thought to contain genetically normal and stable endothelial cells
(ECs), unlike tumor cells, which typically display genetic instability. Yet, chromosomal …

The ability to fuse cells is shared by many viruses, including common human pathogens and
several endogenous viruses. Here we will discuss how cell fusion can link viruses to cancer …

The initiation and progression of cancers reflect the underlying process of somatic evolution,
in which the diversification of heritable phenotypes provides a substrate for natural selection …

The cause of metastasis remains elusive despite vast information on cancer cells. We posit
that cancer cell fusion with macrophages or other migratory bone marrow‐derived cells …

Burkholderia pseudomallei is the causative agent of melioidosis, an infectious disease in the
tropics and subtropics with high morbidity and mortality. The facultative intracellular …