Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis
L Bachs, M Elena, A Parés, C Piera, J Rodés - The Lancet, 1989 - Elsevier
The anti-pruritic effects of rifampicin (10 mg/kg) and phenobarbitone (3 mg/kg) were
assessed in 22 patients with primary biliary cirrhosis in a crossover randomised clinical trial …
assessed in 22 patients with primary biliary cirrhosis in a crossover randomised clinical trial …
Primary biliary cirrhosis and mitochondrial autoantigens—insights from molecular biology
EM Gershwin, RL Coppel, IR Mackay - Hepatology, 1988 - journals.lww.com
Primary biliary cirrhosis (PBC) is an enigmatic chronic liver disease characterized by
progressive inflammatory obliteration of the intrahepatic bile ducts. Many of the clinical …
progressive inflammatory obliteration of the intrahepatic bile ducts. Many of the clinical …
The PBC-specific antigen
H Baum, C Palmer - Molecular aspects of medicine, 1985 - Elsevier
As is reviewed In detail elsewhere in this issue, one of the most characteristic features of
PBC Is a high and persistent titre of'antlmitochondrial antibodies'(AMA). In¢ hls Chapter we …
PBC Is a high and persistent titre of'antlmitochondrial antibodies'(AMA). In¢ hls Chapter we …
Are antimitochondrial antibodies in primary biliary cirrhosis induced by R (rough)-mutants of enterobacteriaceae?
R Stemerowicz, B Möller, A Rodloff, M Freudenberg… - The Lancet, 1988 - Elsevier
Antimitochondrial antibody (AMA)-positive serum samples from 45 patients with primary
biliary cirrhosis (PBC) and AMA-negative serum samples from patients with chronic liver …
biliary cirrhosis (PBC) and AMA-negative serum samples from patients with chronic liver …
[PDF][PDF] Antimitochondrial antibodies in primary biliary cirrhosis recognize both specific peptides and shared epitopes of the M2 family of antigens
GR Flannery, AK Burroughs, P Butler, J Chelliah… - …, 1989 - Wiley Online Library
Sera from patients with primary biliary cirrhosis exhibit variable autoantibody reactivity
against mitochondria, the commonest antigen (designated M2) including three structures of …
against mitochondria, the commonest antigen (designated M2) including three structures of …
Nature of the mitochondrial antigens of primary biliary cirrhosis and their possible relationships to the etiology of the disease
H Baum - Seminars in Liver Disease, 1989 - thieme-connect.com
The original demonstration of high and persistent titers of complement-fixing
antimitochondrial antibodies (AMA) as a diagnostic feature of primary biliary cirrhosis (PBC)' …
antimitochondrial antibodies (AMA) as a diagnostic feature of primary biliary cirrhosis (PBC)' …
Evidence for the cell-surface localization of antigens cross-reacting with the “mitochondrial antibodies” of primary biliary cirrhosis
I Ghadiminejad, H Baum - Hepatology, 1987 - journals.lww.com
Studies with subfractions of Saccharomyces cerevisiae obtained by differential
centrifugation showed only two primary biliary cirrhosis-specific antigens. These antigenic …
centrifugation showed only two primary biliary cirrhosis-specific antigens. These antigenic …
Reaction pattern of mitochondrial antibodies of primary biliary cirrhosis (PBC) is species specific but not organ specific
I Ghadiminejad, H Baum - Journal of Bioenergetics and Biomembranes, 1987 - Springer
The cross reactivity of a well-characterized PBC serum was studied with mitochondria from a
number of sources. These studies were to establish the nonorgan, species specificity of the …
number of sources. These studies were to establish the nonorgan, species specificity of the …
Primary biliary cirrhosis autoantigen and method of use
RL Coppel, ME Gershwin - US Patent 5,891,436, 1999 - Google Patents
Isolated peptides and polypeptides exhibiting the antigenicity of the 70 kD mitochondrial
autoantigen of primary biliary cirrhosis are provided. The peptides, polypeptides and …
autoantigen of primary biliary cirrhosis are provided. The peptides, polypeptides and …
Primary biliary cirrhosis autoantigen
RL Coppel, ME Gershwin - US Patent 5,196,319, 1993 - Google Patents
57 ABSTRACT A DNA molecule is provided which comprises a nucle otide sequence
substantially corresponding to all or a portion of the base sequence coding for the mitochon …
substantially corresponding to all or a portion of the base sequence coding for the mitochon …