The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …

Innate immunity is associated with Alzheimer's disease, but the influence of immune
activation on the production of amyloid-β is unknown,. Here we identify interferon-induced …

Interferon‐induced transmembrane proteins (IFITMs) restrict infections by many viruses, but
a subset of IFITMs enhance infections by specific coronaviruses through currently unknown …

Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to
infection. Sepsis can be caused by a broad range of pathogens; however, bacterial …

Humans display substantial interindividual clinical variability after SARS-CoV-2 infection,–,
the genetic and immunological basis of which has begun to be deciphered. However, the …

In the temperate regions, seasonal influenza virus outbreaks correlate closely with
decreases in humidity. While low ambient humidity is known to enhance viral transmission …

Stem cells are highly resistant to viral infection compared to their differentiated progeny;
however, the mechanism is mysterious. Here, we analyzed gene expression in mammalian …

SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …