Organoids are in vitro self-assembling, organ-like, three-dimensional cellular structures that
stably retain key characteristics of the respective organs. Organoids can be generated from …

Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. It is initially
responsive to cisplatin and carboplatin, two DNA damaging agents used in first line therapy …

Cancer is a major public health problem worldwide. Gastrointestinal cancers account for
approximately one-third of the total global cancer incidence and mortality. Historically, the …

Drug screening—ie, testing the effects of a number of drugs in multiple cell lines—is used for
drug discovery and development, and can also be performed to evaluate the heterogeneity …

Label-free surface-enhanced Raman scattering (SERS) technique with ultra-sensitivity
becomes more and more desirable in biomedical analysis, which is yet hindered by …

Tumor development and progression require chemical and mechanical cues derived from
cellular and non-cellular components in the tumor microenvironment, including the …

Recent developments of organoids engineering and organ-on-a-chip microfluidic
technologies have enabled the recapitulation of the major functions and architectures of …

Background As reported, preclinical animal models differ greatly from the human body. The
evaluation model may be the colossal obstacle for scientific research and anticancer drug …

Microphysiological systems (MPSs) with three-dimensional (3D) cultured models have
attracted considerable interest because of their potential to mimic human health and disease …

Gastrointestinal (GI) infections in sheep have significant implications for animal health,
welfare and productivity, as well as being a source of zoonotic pathogens. Interactions …