The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Progress in clinical and affective neuroscience is redefining psychiatric illness as
symptomatic expression of cellular/molecular dysfunctions in specific brain circuits. Post …

Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

Fear can be an adaptive emotion that helps defend against potential danger. Classical
conditioning models elegantly describe how animals learn which stimuli in the environment …

Fear generalization, in which conditioned fear responses generalize or spread to related
stimuli, is a defining feature of anxiety disorders. The behavioral consequences of …

Abstract Nearly 100 years ago, Ivan Pavlov demonstrated that dogs could learn to use a
neutral cue to predict a biologically relevant event: after repeated predictive pairings …

Exposure-based treatments for clinical anxiety generally are very effective, but relapse is not
uncommon. Likewise, laboratory studies have shown that conditioned fears are easy to …

Background Meta-analytic results of fear-conditioning studies in the anxiety disorders
implicate generalization of conditioned fear to stimuli resembling the conditioned danger …

Objective: Heightened generalization of fear from an aversively reinforced conditioned
stimulus (CS+, a conditioned danger cue) to resembling stimuli is widely accepted as a …