Neutrophils—from bone marrow to first-line defense of the innate immune system

RF Kraus, MA Gruber - Frontiers in immunology, 2021 - frontiersin.org
Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

[HTML][HTML] Targeting the chemokine network in atherosclerosis

Y Yan, M Thakur, EPC van der Vorst, C Weber… - Atherosclerosis, 2021 - Elsevier
Chemokines and their receptors represent a potential target for immunotherapy in chronic
inflammation. They comprise a large family of cytokines with chemotactic activity, and their …

D-dopachrome tautomerase in cardiovascular and inflammatory diseases-A new kid on the block or just another MIF?

C Zan, B Yang, M Brandhofer… - Faseb …, 2022 - epub.ub.uni-muenchen.de
Macrophage migration inhibitory factor (MIF) as well as its more recently described structural
homolog D-dopachrome tautomerase (D-DT), now also termed MIF-2, are atypical cytokines …

Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation

M Brandhofer, A Hoffmann, X Blanchet… - Cellular and Molecular …, 2022 - Springer
To fulfil its orchestration of immune cell trafficking, a network of chemokines and receptors
developed that capitalizes on specificity, redundancy, and functional selectivity. The …

Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells

L Schindler, L Zwissler, C Krammer… - Journal of Leukocyte …, 2021 - academic.oup.com
The chemokine-like inflammatory cytokine macrophage migration inhibitory factor (MIF) is a
pivotal driver of acute and chronic inflammatory conditions, cardiovascular disease …

Gastrointestinal stromal tumors regulate macrophage M2 polarization through the MIF/CXCR4 axis to immune escape

S Xiao, R Xu, Y Yang, R Zhao, Y Xie, X Lei… - Frontiers in …, 2024 - frontiersin.org
Purpose The infiltration of immune cells and their roles of the infiltrating-immune cells in
gastrointestinal stromal tumor (GIST) is still unclear. We aimed to discover the infiltration cell …

Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice

C Krammer, B Yang, S Reichl… - The FASEB …, 2023 - epub.ub.uni-muenchen.de
Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice Page 1 The
FASEB Journal. 2023;37:e22752. | 1 of 26 https://doi.org/10.1096/fj.202200056R …

Lasso-grafted designer cytokines

A Kapurniotu, J Bernhagen - Nature Biomedical Engineering, 2023 - nature.com
Lasso-grafted designer cytokines | Nature Biomedical Engineering Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

[HTML][HTML] MIF 在慢性肾脏病患者中发生心血管事件的相关性

李思莹, 刘珍 - Advances in Clinical Medicine, 2023 - hanspub.org
慢性肾脏病(CKD) 现在被认为是心血管疾病(CVD) 的独立危险因素. 而慢性肾脏病发生心血管
事件的机制主要包括: 肾素–血管紧张素–醛固酮系统异常激活(RAAS), 氧化应激, 炎症反应 …

Characterization of Plasmodium falciparum macrophage migration inhibitory factor homologue and its cysteine deficient mutants

S Schipper, E Springer, J Hahn, S Rahlfs… - Parasitology …, 2022 - Elsevier
Plasmodium falciparum macrophage migration inhibitory factor (PfMIF) is a homologue of
the multifunctional human host cytokine MIF (HsMIF). Upon schizont rupture it is released …