[HTML][HTML] Spermatogonial stem cells and spermatogenesis in mice, monkeys and men
Continuous spermatogenesis in post-pubertal mammals is dependent on spermatogonial
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …
stem cells (SSCs), which balance self-renewing divisions that maintain stem cell pool with …
International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors
The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …
The adult human testis transcriptional cell atlas
Human adult spermatogenesis balances spermatogonial stem cell (SSC) self-renewal and
differentiation, alongside complex germ cell-niche interactions, to ensure long-term fertility …
differentiation, alongside complex germ cell-niche interactions, to ensure long-term fertility …
Chromatin and single-cell RNA-seq profiling reveal dynamic signaling and metabolic transitions during human spermatogonial stem cell development
Human adult spermatogonial stem cells (hSSCs) must balance self-renewal and
differentiation. To understand how this is achieved, we profiled DNA methylation and open …
differentiation. To understand how this is achieved, we profiled DNA methylation and open …
Application of stem cell therapy for infertility
S Saha, P Roy, C Corbitt, SS Kakar - Cells, 2021 - mdpi.com
Infertility creates an immense impact on the psychosocial wellbeing of affected couples,
leading to poor quality of life. Infertility is now considered to be a global health issue …
leading to poor quality of life. Infertility is now considered to be a global health issue …
Spermatogonial stem cells for in vitro spermatogenesis and in vivo restoration of fertility
F Ibtisham, A Honaramooz - Cells, 2020 - mdpi.com
Spermatogonial stem cells (SSCs) are the only adult stem cells capable of passing genes
onto the next generation. SSCs also have the potential to provide important knowledge …
onto the next generation. SSCs also have the potential to provide important knowledge …
[HTML][HTML] Fluorescence-and magnetic-activated cell sorting strategies to isolate and enrich human spermatogonial stem cells
H Valli, M Sukhwani, SL Dovey, KA Peters, J Donohue… - Fertility and sterility, 2014 - Elsevier
Objective To determine the molecular characteristics of human spermatogonia and optimize
methods to enrich spermatogonial stem cells (SSCs). Design Laboratory study using human …
methods to enrich spermatogonial stem cells (SSCs). Design Laboratory study using human …
Fertility preservation for prepubertal boys: lessons learned from the past and update on remaining challenges towards clinical translation
BACKGROUND Childhood cancer incidence and survivorship are both on the rise.
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
However, many lifesaving treatments threaten the prepubertal testis. Cryopreservation of …
Endogenous, very small embryonic-like stem cells: critical review, therapeutic potential and a look ahead
D Bhartiya, A Shaikh, S Anand, H Patel… - Human …, 2017 - academic.oup.com
BACKGROUND Both pluripotent very small embryonic-like stem cells (VSELs) and induced
pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for …
pluripotent stem (iPS) cells were reported in 2006. In 2012, a Nobel Prize was awarded for …
Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro
Spermatogonial stem cells (SSCs) are essential for the generation of sperm and have
potential therapeutic value for treating male infertility, which afflicts> 100 million men world …
potential therapeutic value for treating male infertility, which afflicts> 100 million men world …