BACKGROUND: The CD4 cell count at which combination antiretroviral therapy should be
started is a central, unresolved issue in the care of HIV-1-infected patients. In the absence of …

Heart failure is a progressive disease that now affects 5 million patients in the United States.
Recent estimates suggest that between 5% and 10% of all patients with heart failure (HF) …

Background Health care for people living with HIV has improved substantially in the past two
decades. Robust estimates of how these improvements have affected prognosis and life …

In solid tumors, targeted treatments can lead to dramatic regressions, but responses are
often short-lived because resistant cancer cells arise. The major strategy proposed for …

The burden of disease and injury in Australia 2003 Page 1 The burden of disease and injury in
Australia 2003 AUTHOR(S) S Begg, T Vos, B Barker, Christopher Stevenson, L Stanley, A …

Objective: To estimate the effect of combined antiretroviral therapy (cART) on mortality
among HIV-infected individuals after appropriate adjustment for time-varying confounding by …

Objective: To compare life expectancies between recently diagnosed HIV-infected patients
and age and sex-matched uninfected individuals from the general population. Design …

Context Mortality among human immunodeficiency virus (HIV)–infected individuals has
decreased dramatically in countries with good access to treatment and may now be close to …

Importance Substance use is a major driver of the HIV epidemic and is associated with poor
HIV care outcomes. Patient navigation (care coordination with case management) and the …

During the extended clinically latent period associated with Human Immunodeficiency Virus
(HIV) infection the virus itself is far from latent. This phase of infection generally comes to an …