Atrial septal defects are the third most common type of congenital heart disease. Included in
this group of malformations are several types of atrial communications that allow shunting of …

Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and is associated
with a number of deleterious phenotypes, including learning disability, heart defects, early …

Abstract Objective To update the 2011 Canadian guidelines for primary care of adults with
intellectual and developmental disabilities (IDD). Methods Family physicians and other …

El síndrome de Down es la cromosomopatía más común del ser humano, con una
frecuencia de 1 en 650 recién nacidos vivos. Las manifestaciones clínicas son muy …

We aimed to assess the frequency of chromosomal abnormalities among infants with
congenital heart defects (CHDs) in an analysis of population-based surveillance data. We …

BACKGROUND: As a result of antenatal screening, abortion of fetuses with Down syndrome
has become increasingly common. Little is known about the cardiovascular phenotype in …

Down syndrome (DS) is caused by trisomy of human chromosome 21 (Hsa21). DS is a gene
dosage disorder that results in multiple phenotypes including congenital heart defects. This …

BACKGROUND AND OBJECTIVES: Children with Down syndrome (DS) have lower birth
weights and grow more slowly than children without DS. Advances in and increased access …

Congenital heart disease (CHD) affects nearly 1% of the population. It is a complex disease,
which may be caused by multiple genetic and environmental factors. Studies in human …

The aim of this study was to assess the prevalence of congenital heart defects (CHDs) and
persistent pulmonary hypertension of the neonate (PPHN) in children with Down syndrome …