Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Challenges and perspectives of DNA nanostructures in biomedicine

A Keller, V Linko - Angewandte Chemie International Edition, 2020 - Wiley Online Library
DNA nanotechnology holds substantial promise for future biomedical engineering and the
development of novel therapies and diagnostic assays. The subnanometer‐level …

Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA–Lipid …

J Szebeni, B Kiss, T Bozó, K Turjeman… - ACS …, 2023 - ACS Publications
Despite the worldwide success of mRNA-LNP Covid-19 vaccines, the nanoscale structures
of these formulations are still poorly understood. To fill this gap, we used a combination of …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Lipid-based nanoparticle formulations for small molecules and RNA drugs

LM Ickenstein, P Garidel - Expert opinion on drug delivery, 2019 - Taylor & Francis
Introduction: Liposomes and lipid-based nanoparticles (LNPs) effectively deliver cargo
molecules to specific tissues, cells, and cellular compartments. Patients benefit from these …

pH-triggered controlled drug release from mesoporous silica nanoparticles via intracelluar dissolution of ZnO nanolids

F Muhammad, M Guo, W Qi, F Sun… - Journal of the …, 2011 - ACS Publications
Acid-decomposable, luminescent ZnO quantum dots (QDs) have been employed to seal the
nanopores of mesoporous silica nanoparticles (MSNs) in order to inhibit premature drug …

Coordination-responsive drug release inside gold nanorod@ metal-organic framework core–shell nanostructures for near-infrared-induced synergistic chemo …

Y Li, J Jin, D Wang, J Lv, K Hou, Y Liu, C Chen, Z Tang - Nano Research, 2018 - Springer
Multifunctional core–shell nanostructures formed by integration of distinct components have
received wide attention as promising biological platforms in recent years. In this work …

Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound

H Grüll, S Langereis - Journal of Controlled Release, 2012 - Elsevier
In the continuous search for cancer therapies with a higher therapeutic window, localized
temperature-induced drug delivery may offer a minimal invasive treatment option. Here, a …

Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems

J Kuntsche, JC Horst, H Bunjes - International journal of pharmaceutics, 2011 - Elsevier
Cryogenic transmission electron microscopy (cryo-TEM) has evolved into an indispensable
tool for the characterization of colloidal drug delivery systems. It can be applied to study the …

The liposomal formulation of doxorubicin

SA Abraham, DN Waterhouse, LD Mayer… - Methods in …, 2005 - Elsevier
Doxorubicin is the best known and most widely used member of the anthracycline antibiotic
group of anticancer agents. It was first introduced in the 1970s, and since that time has …