The role of cytochrome P450s in insect toxicology and resistance

R Nauen, C Bass, R Feyereisen… - Annual Review of …, 2022 - annualreviews.org
Insect cytochrome P450 monooxygenases (P450s) perform a variety of important
physiological functions, but it is their role in the detoxification of xenobiotics, such as natural …

[HTML][HTML] The molecular mechanisms of insecticide resistance in aphid crop pests

C Bass, R Nauen - Insect Biochemistry and Molecular Biology, 2023 - Elsevier
Aphids are a group of hemipteran insects that include some of the world's most economically
important agricultural pests. The control of pest aphids has relied heavily on the use of …

Divergent amplifications of CYP9A cytochrome P450 genes provide two noctuid pests with differential protection against xenobiotics

Y Shi, Q Liu, W Lu, J Yuan, Y Yang… - Proceedings of the …, 2023 - National Acad Sciences
Here, we provide mechanistic support for the involvement of the CYP9A subfamily of
cytochrome P450 monooxygenases in the detoxification of host plant defense compounds …

Rapid adaptation in a fast‐changing world: Emerging insights from insect genomics

GA McCulloch, JM Waters - Global Change Biology, 2023 - Wiley Online Library
Many researchers have questioned the ability of biota to adapt to rapid anthropogenic
environmental shifts. Here, we synthesize emerging genomic evidence for rapid insect …

[HTML][HTML] Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus …

A Pym, PA Umina, J Reidy-Crofts, BJ Troczka… - Insect Biochemistry and …, 2022 - Elsevier
The green peach aphid, Myzus persicae, is a highly damaging, globally distributed crop pest
that has evolved multiple resistance to numerous insecticides. It is thus imperative that …

Molecular mechanisms underlying host plant specificity in aphids

PY Shih, A Sugio, JC Simon - Annual Review of Entomology, 2023 - annualreviews.org
Aphids are serious pests of agricultural and ornamental plants and important model systems
for hemipteran–plant interactions. The long evolutionary history of aphids with their host …

[HTML][HTML] An aphid-secreted salivary protease activates plant defense in phloem

H Guo, Y Zhang, J Tong, P Ge, Q Wang, Z Zhao… - Current Biology, 2020 - cell.com
Recent studies have reported that aphids facilitate their colonization of host plants by
secreting salivary proteins into host tissues during their initial probing and feeding. Some of …

Functional Validation of the Roles of Cytochrome P450s in Tolerance to Thiamethoxam and Imidacloprid in a Field Population of Aphis gossypii

Y Lv, S Wen, Y Ding, X Gao, X Chen… - Journal of Agricultural …, 2022 - ACS Publications
Field populations of Aphis gossypii (SDR) have evolved high resistance to neonicotinoids,
including thiamethoxam and imidacloprid. Synergism bioassays and transcriptomic …

Insights into the effects of insecticides on aphids (Hemiptera: Aphididae): Resistance mechanisms and molecular basis

RM Kaleem Ullah, F Gao, A Sikandar, H Wu - International Journal of …, 2023 - mdpi.com
With the passage of time and indiscreet usage of insecticides on crops, aphids are
becoming resistant to their effect. The different classes of insecticides, including …

Molecular innovations underlying resistance to nicotine and neonicotinoids in the aphid Myzus persicae

BJ Troczka, KS Singh, CT Zimmer… - Pest Management …, 2021 - Wiley Online Library
The green peach aphid, Myzus persicae, is a globally distributed highly damaging crop pest.
This species has demonstrated an exceptional ability to evolve resistance to both synthetic …