The Golgi apparatus (GA) is involved in a whole spectrum of activities, from lipid
biosynthesis and membrane secretion to the posttranslational processing and trafficking of …

The rate of discovery and increased understanding of genetic causes for
neurodevelopmental disorders has peaked over the past decade. It is well recognised that …

Purpose Malformations of cortical development (MCD) are a phenotypically and genetically
heterogeneous group of disorders, for which the diagnostic rate of genetic testing in a …

Mutations in ADP-ribosylation factor guanine nucleotide-exchange factor 2 (ARFGEF2) gene
was recently recognized to cause bilateral periventricular nodular heterotopia, putaminal …

Disorders of the developing nervous system may be of genetic origin, comprising congenital
malformations of spine and brain as well as metabolic or vascular disorders that affect …

Membrane traffic between secretory and endosomal compartments is vesicle‐mediated and
must be tightly balanced to maintain a physiological compartment size. Vesicle formation is …

Background Heterotopias are a neuronal migration disorder caused by extrinsic factors or by
genetic mutations. When the location is periventricular, the most frequent genetic cause is …

Background Head circumference is associated with intelligence and tracks from childhood
into adulthood. Methods We performed a genome-wide association study meta-analysis and …

There has been a traditional conceptual partition between the so-called non-lesional genetic
epilepsies and the genetically determined interposed epileptogenic structural abnormalities …

Neural proliferation, migration and differentiation require reorganization of the actin
cytoskeleton and regulation of vesicle trafficking to provide stability in maintaining cell …