A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

[HTML][HTML] Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

B Lomonte, JJ Calvete - Journal of Venomous Animals and Toxins …, 2017 - SciELO Brasil
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …

[PDF][PDF] Antivenomics and its role in enhancing cobra envenomation treatments: A review of current practices and future prospects

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

L Ledsgaard, J Wade, TP Jenkins, K Boddum… - Nature …, 2023 - nature.com
Snakebite envenoming continues to claim many lives across the globe, necessitating the
development of improved therapies. To this end, broadly-neutralizing human monoclonal …

[PDF][PDF] Innovative approaches to neutralizing cobra venom: Advances in antivenomics and recombinant antivenoms

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

Convergent evolution of pain-inducing defensive venom components in spitting cobras

TD Kazandjian, D Petras, SD Robinson, J van Thiel… - Science, 2021 - science.org
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …

From fangs to pharmacology: the future of snakebite envenoming therapy

AH Laustsen, M Engmark, C Milbo… - Current …, 2016 - ingentaconnect.com
The snake is the symbol of medicine due to its association with Asclepius, the Greek God of
medicine, and so with good reasons. More than 725 species of venomous snakes have …

Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)

CH Tan, KY Tan, SY Fung, NH Tan - BMC genomics, 2015 - Springer
Abstract Background The king cobra (Ophiophagus hannah) is widely distributed throughout
many parts of Asia. This study aims to investigate the complexity of Malaysian Ophiophagus …

Proteomics and antivenomics of Echis carinatus carinatus venom: Correlation with pharmacological properties and pathophysiology of envenomation

A Patra, B Kalita, A Chanda, AK Mukherjee - Scientific reports, 2017 - nature.com
The proteome composition of Echis carinatus carinatus venom (ECV) from India was studied
for the first time by tandem mass spectrometry analysis. A total of 90, 47, and 22 distinct …

Current technology for the industrial manufacture of snake antivenoms

G León, M Vargas, Á Segura, M Herrera, M Villalta… - Toxicon, 2018 - Elsevier
Snake antivenoms are formulations of animal immunoglobulins used in the treatment of
snakebite envenomation. The general scheme for producing snake antivenoms has …