Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential

P Liu, Y Mao, Y Xie, J Wei, J Yao - Stem Cell Research & Therapy, 2022 - Springer
Cost-effective treatment strategies for liver fibrosis or cirrhosis are limited. Many clinical trials
of stem cells for liver disease shown that stem cells might be a potential therapeutic …

Exploring the bone marrow micro environment in thalassemia patients: Potential therapeutic alternatives

Z Li, X Yao, J Zhang, J Yang, J Ni, Y Wang - Frontiers in Immunology, 2024 - frontiersin.org
Genetic mutations in the β-globin gene lead to a decrease or removal of the β-globin chain,
causing the build-up of unstable alpha-hemoglobin. This condition is referred to as beta …

[HTML][HTML] Targeting Reprogrammed Cancer-Associated Fibroblasts with Engineered Mesenchymal Stem Cell Extracellular Vesicles for Pancreatic Cancer Treatment

P Zhou, X Ding, X Du, L Wang, Y Zhang - Biomaterials Research, 2024 - spj.science.org
Background: As one of the most aggressive and lethal cancers, pancreatic cancer is highly
associated with cancer-associated fibroblasts (CAFs) that influence the development and …

[HTML][HTML] Thalassemia: Pathophysiology, diagnosis, and advances in treatment

IZ Sadiq, FS Abubakar, HS Usman, AD Abdullahi… - Thalassemia …, 2024 - mdpi.com
Thalassemia represents a diverse group of inherited hematological disorders characterized
by defective globin chain synthesis, leading to chronic anemia and associated …

Long-term experience with biohybrid cochlear implants in human neurosensory restoration

DM Fenov, R Salcher, E Kludt… - Cochlear Implants …, 2024 - Taylor & Francis
Objective The implantation of biohybrid electrodes was introduced a few years ago in our
clinic. These electrodes coated with autologous mononuclear cells releasing anti …

外周血干细胞移植治疗重型地中海贫血的相关并发症及死亡原因分析

黄楚雯, 江华, 李敏清 - 中国组织工程研究, 2023 - cjter.com
外周血干细胞移植治疗重型地中海贫血的相关并发症及死亡原因分析 Page 1 42|中国组织工程
研究|第27卷|第1期|2023年1月 中国组织工程研究 Chinese Journal of Tissue Engineering …

Immune response: the Achilles' heel of the stem cell-based regenerative therapies

CS Oliveira, FK Tavaria - Exploration of Immunology, 2023 - repositorio.ucp.pt
Besides trauma, several pathological conditions which directly affect the normal functioning
of organs, require new therapeutic strategies to repair damaged or diseased tissues. Tissue …

Evaluation of hepatic fibrosis by transient elastography in βthalassemia children before and after hematopoietic stem cell transplantation

R Salama, E Elhawary, D Ziada… - The Egyptian Journal …, 2023 - journals.lww.com
Background Iron overload is a major concern in all patients with transfusion-dependent
thalassemia (TDT). The liver, being a target for iron deposition is at risk of developing liver …

Complications and death causes of peripheral blood stem cell transplantation in the treatment of thalassemia major

C Huang, H Jiang, M Li - Chinese Journal of Tissue Engineering Research, 2023 - cjter.com
BACKGROUND: Allogeneic hematopoietic stem cell transplantation is the only effective
method to cure thalassemia major. However, the risk factors influencing the prognosis of …