Recognizing the presence of invading pathogens is key to mounting an effective innate
immune response. Mammalian cells express different classes of germline-encoded pattern …

Malaria remains a highly prevalent disease in more than 90 countries and accounts for at
least 1 million deaths every year. Plasmodium falciparum infection is often associated with a …

Gut microbiome plays an essential role in modulating host immune responses. However,
little is known about the interaction of microbiota, their metabolites and relevant inflammatory …

Carbohydrate structures that decorate the surface of cells are increasingly recognized as
playing important roles in the biology of host–pathogen interactions. Plasmodium species …

The mechanisms of malarial anemia induction are poorly understood, but cytokines and
autoantibodies are considered to play important roles. This work aimed at evaluating the …

Pulmonary complication in severe Plasmodium falciparum malaria is manifested as a
prolonged impairment of gas transfer or the more severe acute respiratory distress …

Background Reperfusion injury is one of the leading causes of myocardial cell death and
heart failure. This study was performed to identify new candidate lipid biomarkers for the …

Intrauterine growth restriction (IUGR) severely impairs fetal development and offspring
health. Odd-chain fatty acid (OCFA) possess beneficial biological activities in regulating …

Objective—The coagulation-inflammation cycle has been implicated as a critical component
in malaria pathogenesis. Defibrotide (DF), a mixture of DNA aptamers, displays …

Metabolomics refers to top-down systems biological analysis of metabolites in biological
specimens. Phenotypic proximity of metabolites makes them interesting candidates for …