Significance and potential role of eosinophils in non-cystic fibrosis bronchiectasis

W Guan, G Oscullo, M He, D Xu… - The Journal of Allergy …, 2023 - Elsevier
Bronchiectasis is a complex and heterogeneous disease with a myriad of pulmonary and
extrapulmonary etiologies. Bronchiectasis has a predominantly neutrophilic inflammatory …

Dupilumab's Impact on Blood Parameters in Nasal Polyposis: 18‐Month Follow‐Up in Real Life

A Loperfido, A Ciofalo, C Cavaliere… - Journal of …, 2023 - Wiley Online Library
Background. Dupilumab represents the first approved biological for severe uncontrolled
chronic rhinosinusitis with nasal polyps (CRSwNP). Objective. Aim of this paper is to provide …

The mechanism of action and clinical efficacy of low-dose long-term macrolide therapy in chronic rhinosinusitis

G Ryu, E Lee, SI Park, M Park, SD Hong… - International Journal of …, 2023 - mdpi.com
Various chronic inflammatory airway diseases can be treated with low-dose, long-term
(LDLT) macrolide therapy. LDLT macrolides can be one of the therapeutic options for …

Long-Term Perspectives on Chronic Rhinosinusitis with Nasal Polyps: Evaluating Recurrence Rates after Functional Endoscopic Sinus Surgery in the Biologics Era …

C Cavaliere, S Masieri, E Begvarfaj… - Journal of Personalized …, 2024 - mdpi.com
Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory disease
with multifactorial etiopathogenesis. This study investigated the recurrence rate and risk …

A Novel Model of Staphylococcus aureus-Induced Lymphoplasmacytic Rhinosinusitis in Rats

W Murphy, S Liu, K Hon, J Finnie, GS Bouras… - International Journal of …, 2024 - mdpi.com
Chronic rhinosinusitis (CRS) is characterized by sinonasal mucosal inflammation.
Staphylococcus aureus (S. aureus) is associated with severe CRS phenotypes. Different …

Increased CYR61 expression activates CCND1/c-Myc pathway to promote nasal epithelial cells proliferation in chronic rhinosinusitis with nasal polyps

C Luo, Y Zhu, J Zhou, X Sun, S Zhang, S Tan, Z Li… - Clinical …, 2023 - Elsevier
Purpose Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is a chronic sinonasal
inflammatory disease characterized histologically by hyperplastic nasal epithelium and …

Use of low-level laser therapy for patients with chronic rhinosinusitis: a single-blind, sham-controlled clinical trial

S Naghdi, NN Ansari, M Varedi, M Fathali… - Lasers in Medical …, 2022 - Springer
Chronic rhinosinusitis (CRS) is one of the most common conditions all over the world. The
purpose of this study was to investigate the effects of low-level laser therapy (LLLT) in …

Real-Life Evidence of Mepolizumab Treatment in Chronic Rhinosinusitis with Nasal Polyps: A Multicentric Study

C Cavaliere, A Loperfido, A Ciofalo… - Journal of Clinical …, 2024 - mdpi.com
Background: The introduction of biological drugs in the management of chronic
rhinosinusitis with nasal polyps (CRSwNP) is allowing new and increasingly promising …

The anti-inflammatory role of therapeutic ultrasound and low-level laser in chronic rhinosinusitis: A fractional exhaled nitric oxide outcome hypothesis

M Kashi-Alashti, NN Ansari, S Naghdi, M Fathali… - Medical …, 2024 - Elsevier
Chronic rhinosinusitis is defined as a complex of disorders whose main feature is nasal and
paranasal sinus mucosal inflammation for at least three months. Inflammation plays a key …

A clinical study on the relationship between chronic rhinosinusitis and bronchial asthma

J Kang, H Yong, Z Zhang, J Liu, X Gao, H Shao… - Frontiers in …, 2024 - frontiersin.org
Objective To investigate the correlation between chronic rhinosinusitis (CRS) and bronchial
asthma, focusing on the CRS without nasal polyps (CRSsNP) and CRS with nasal polyps …