[HTML][HTML] Matrix stiffness triggers lipid metabolic cross-talk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases

Y Zheng, R Zhou, J Cai, N Yang, Z Wen, Z Zhang… - Cancer Research, 2023 - AACR
Bevacizumab is an anti-VEGF monoclonal antibody that plays an important role in the
combination treatment of advanced colorectal cancer. However, resistance remains a major …

Single-cell atlas reveals the hemocyte subpopulations and stress responses in asian giant softshell turtle during hibernation

X Hong, Y Wang, K Wang, C Wei, W Li, L Yu, H Xu… - Biology, 2023 - mdpi.com
Simple Summary Hibernation in turtle species is an adaptive survival strategy to colder
winter conditions or food restrictions. However, the mechanisms underlying seasonal …

[HTML][HTML] Evolution of diapause in the African turquoise killifish by remodeling the ancient gene regulatory landscape

PP Singh, GA Reeves, K Contrepois, K Papsdorf… - Cell, 2024 - cell.com
Suspended animation states allow organisms to survive extreme environments. The African
turquoise killifish has evolved diapause as a form of suspended development to survive a …

[PDF][PDF] Research Progress of Cadmium Toxicity on Male Reproduction Health

S Tunio, FA Ujjan, M Memon, SA Fazlani… - J Biomed Sci …, 2024 - oaskpublishers.com
Cadmium is an element of heavy metal which can be harmful to environment and human
beings with the rapid development of industry, cadmium as an important raw material …

Comparative analysis for nutrients, flavor compounds, and lipidome reveal the edible value of pond-cultured male Pelodiscus sinensis with different ages

M Hou, W Sun, Y Ma, H Ye, X Zhai, Y Xue, R Tang… - Food Chemistry, 2024 - Elsevier
Pelodiscus sinensis is an aquatic product with a long growth cycle in pond culture and high
nutritional value meat. The flavor compounds, nutrients, and lipidome were investigated to …

Effect of cadmium on the regulatory mechanism of steroidogenic pathway of Leydig cells during spermatogenesis

HL Ji, W Fan, M Kakar, RA Alajmi… - … Zoology Part A …, 2024 - Wiley Online Library
Cadmium is a male reproductive toxicant that interacts with a variety of pathogenetic
mechanisms. However, the effect of cadmium on the regulatory mechanism of the …

Effects of creatine treatment at low temperature on the development of ovarian follicles before sexual maturity in Pelodiscus sinensis

G Zhang, Y Liu, Y Li, J Tian, Y Zhu, G Qian, Z Chen… - Aquaculture, 2025 - Elsevier
As a nitrogen-containing organic acid, creatine can stabilize cellular adenosine triphosphate
(ATP) levels and promote growth. For reptiles with hibernation habits, creatine has a special …

Seasonal exploration of ultrastructure and Na+/K+-ATPase, Na+/K+/2Cl–cotransporter of mitochondria-rich cells in the small intestine of turtles

WA Vistro, I Tarique, A Haseeb, P Yang, Y Huang… - Micron, 2019 - Elsevier
Despite the exploration of mitochondria-rich cells (MRCs) in different animal classes, very
limited information has been documented about MRCs in reptiles. The present study was …

Aggravation of hepatic lipidosis in red-footed tortoise Chelonoidis carbonaria with age is associated with alterations in liver mitochondria

MR Sartori, CDC Navarro, RF Castilho… - … and Physiology Part B …, 2022 - Elsevier
The occurrence of hepatic lipidosis is commonly reported in different reptilian species,
especially in animals under captivity. Liver accumulation of fat is associated with disorders …

In vivo autophagy up-regulation of small intestine enterocytes in chinese soft-shelled turtles during hibernation

WA Vistro, Y Zhang, X Bai, P Yang, Y Huang, W Qu… - Biomolecules, 2019 - mdpi.com
Many studies have focused on how autophagy plays an important role in intestinal
homeostasis under pathological conditions. However, its role in the intestine during …