BACKGROUND Chromosomal mosaicism, the presence of two or more distinct cell lines, is
prevalent throughout human pre-and post-implantation development and can lead to …

Eggs and sperm develop through a specialized cell division called meiosis. During meiosis,
the number of chromosomes is reduced by two sequential divisions in preparation for …

ABSTRACT BACKGROUND The unbalanced transmission of chromosomes in human
gametes and early preimplantation embryos causes aneuploidy, which is a major cause of …

OBJECTIVE: To validate and determine the best array–comparative genomic hybridization
(aCGH; array-CGH) protocols for preimplantation genetic screening (PGS). DESIGN …

This study presents the world's largest series of over 20,000 oocytes tested for aneuploidies,
involving chromosomes 13, 16, 18, 21 and 22, providing the data on the rates and types of …

Abstract The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held
to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted …

Female meiosis is comprised by two cell divisions, meiosis I (MI) and II (MII) and two different
stages at which the development of the oocyte is temporarily halted. In the case of MI, this …

BACKGROUND The first week of human embryonic development comprises a series of
events that change highly specialized germ cells into undifferentiated human embryonic …

At least 50% of human embryos are abnormal, and that increases to 80% in women 40
years or older. These abnormalities result in low implantation rates in embryos transferred …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …