Proteins belonging to the 'A Disintegrin And Metalloproteinase'(ADAM) family are membrane-
anchored proteases that are able to cleave the extracellular domains of several membrane …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Cadherins mediate cell–cell adhesion but are also involved in intracellular signaling
pathways associated with neuropsychiatric disease. Most of the∼ 100 cadherins that are …

The role of glia in modulating neuronal network activity is an important question.
Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane …

As a member of the A Disintegrin And Metalloproteinase (ADAM) family, ADAM10 has been
identified as the constitutive α-secretase in the process of amyloid-β protein precursor …

Abstract 'A disintegrin and metalloproteases'(ADAMs) are a family of transmembrane
proteins with diverse functions in multicellular organisms. About half of the ADAMs are active …

After spinal cord injury (SCI), endogenous neural/progenitor stem cells (NSPCs) were
activated in neural tissue adjacent to the injured segment, but few cells migrated to the injury …

The synapse is the locus of plasticity where short-term alterations in synaptic strength are
converted to long-lasting memories. In addition to the presynaptic terminal and the …

The inhospitable niche at the injury site after spinal cord injury (SCI) brings several
challenges to neural stem cell (NSC) therapy, such as limited NSC retention and neuronal …

The metalloproteinase ADAM10 is of importance for Notch-dependent cortical brain
development. The protease is tightly linked with α-secretase activity toward the amyloid …