Extracellular vesicles as personalized medicine
Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …
intercellular communication network that contributes to health and disease. The contents of …
Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma
X Guo, R Sui, H Piao - Journal of Nanobiotechnology, 2022 - Springer
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and
proteins and are involved in intercellular communication and function, playing an essential …
proteins and are involved in intercellular communication and function, playing an essential …
Combination therapy comprising paclitaxel and 5-fluorouracil by using folic acid functionalized bovine milk exosomes improves the therapeutic efficacy against breast …
Paclitaxel (PAC) has been approved by FDA for clinical use (Taxol®), yet dose-dependent
severe toxicity due to the adjuvant Cremophor EL® in combination with ethanol is a major …
severe toxicity due to the adjuvant Cremophor EL® in combination with ethanol is a major …
Membrane protein modification modulates big and small extracellular vesicle biodistribution and tumorigenic potential in breast cancers in vivo
Extracellular vesicles (EVs) are released by cells to mediate intercellular communication
under pathological and physiological conditions. While small EVs (sEVs;< 100–200 nm …
under pathological and physiological conditions. While small EVs (sEVs;< 100–200 nm …
[HTML][HTML] Exosomal transfer leads to chemoresistance through oxidative phosphorylation-mediated stemness phenotype in colorectal cancer
Background: Recently years have seen the increasing evidence identifying that OXPHOS is
involved in different processes of tumor progression and metastasis and has been proposed …
involved in different processes of tumor progression and metastasis and has been proposed …
[HTML][HTML] Extracellular vesicle-mediated transport: Reprogramming a tumor microenvironment conducive with breast cancer progression and metastasis
D Brena, MB Huang, V Bond - Translational oncology, 2022 - Elsevier
Breast cancer metastatic progression to critical secondary sites is the second leading cause
of cancer-related mortality in women. While existing therapies are highly effective in …
of cancer-related mortality in women. While existing therapies are highly effective in …
Exosomes in bone remodeling and breast cancer bone metastasis
Exosomes are endosome-derived microvesicles that carry cell-specific biological cargo,
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …
[HTML][HTML] Exosomes: Insights and therapeutic applications in cancer
AR Panigrahi, L Srinivas, J Panda - Translational Oncology, 2022 - Elsevier
Cancer refers to the division of abnormal cells at an uncontrollable rate that possesses the
ability to infiltrate and destroy normal tissues. It frequently spreads to normal tissues …
ability to infiltrate and destroy normal tissues. It frequently spreads to normal tissues …
Extracellular vesicles: A new diagnostic biomarker and targeted drug in osteosarcoma
X Gao, B Gao, S Li - Frontiers in Immunology, 2022 - frontiersin.org
Osteosarcoma (OS) is a primary bone cancer that is highly prevalent among adolescents
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
and adults below the age of 20 years. The prognostic outcome of metastatic OS or relapse is …
[HTML][HTML] Liquid Biopsies: Emerging role and clinical applications in solid tumours
Late detection and lack of precision diagnostics are the major challenges in cancer
prevention and management. Biomarker discovery in specific cancers, especially at the pre …
prevention and management. Biomarker discovery in specific cancers, especially at the pre …