Drug addiction is a chronic relapsing disorder, and a significant amount of research has
been devoted to understand the factors that contribute to the development, loss of control …

Background Comorbidity of anxiety disorders, stressor-and trauma-related disorders, and
substance use disorders is extremely common. Moreover, therapies that reduce pathological …

Results from clinical studies suggest that drug relapse and craving are often provoked by
exposure to drug-associated contexts. Since 2002, this phenomenon has been modeled in …

Alcohol use disorder (AUD) and (PTSD) frequently co-occur and individuals suffering from
this dual diagnosis often exhibit increased symptom severity and poorer treatment outcomes …

The biological stress response of the body forms one of the foundations of adaptive
behavior, including promoting (and impairing) different forms of memory. This response …

The basolateral amygdala (BLA) is a critical site for the reconsolidation of labile contextual
cocaine memories following retrieval-induced reactivation/destabilization. Here, we …

Methamphetamine (METH) addiction is a growing epidemic worldwide. It is a common
psychiatric disease and stress has an important role in the drug seeking and relapse …

Rationale In rodents, environmental enrichment (EE) produces both preventive and curative
effects on drug addiction, and this effect is believed to depend at least in part on EE's actions …

Sex differences in patterns of methamphetamine (MA) abuse have been reported with
females (humans and rodents) showing an elevated addiction phenotype. Previous findings …

Background The delineation of the behavioral neurobiological mechanisms underlying the
heterogeneous pathways for alcohol use disorders (AUDs) is ostensibly imperative for the …