Organoids are in vitro 3D models that maintain their own tissue structure and function. They
largely overcome the limitations of traditional tumor models and have become a powerful …

Polyploid giant cancer cells (PGCCs) are characterized by the presence of either a single
enlarged nucleus or multiple nuclei and are closely associated with tumor progression and …

Therapeutic resistance in cancer significantly contributes to mortality, with many patients
eventually experiencing recurrence after initial treatment responses. Recent studies have …

PARPi is currently the most important breakthrough in the treatment of ovarian cancer in
decades, and it has been integrated into the initial maintenance therapy for ovarian cancer …

Multiple cancers exhibit aberrant protein arginine methylation by both type I arginine
methyltransferases, predominately protein arginine methyltransferase 1 (PRMT1) and to a …

Polyploid giant cancer cells (PGCC) are frequently detected in tumors and are increasingly
recognized for their roles in chromosomal instability and associated genome evolution that …

The advent of targeted therapies has led to tremendous improvements in treatment options
and their outcomes in the field of oncology. Yet, many cancers outsmart precision drugs by …

Despite progress in cancer immunotherapy, ovarian cancer (OC) prognosis continues to be
disappointing. Recent studies have shed light on how not just tumour cells, but also the …

Based on the snap‐through instability, the pursuit for mechanical metamaterials with flexible
functional applications and the ability to combine with information has been the Holy Grail …

The capacity of cancer cells to migrate from a primary tumor, disseminate throughout the
body, and eventually establish secondary tumors is a fundamental aspect of metastasis. A …