Fluid dynamics in the HeartMate 3: influence of the artificial pulse feature and residual cardiac pulsation

L Wiegmann, B Thamsen, D De Zélicourt… - Artificial …, 2019 - Wiley Online Library
Ventricular assist devices (VADs), among which the HeartMate 3 (HM3) is the latest clinically
approved representative, are often the therapy of choice for patients with end‐stage heart …

Insights into the low rate of in-pump thrombosis with the heartmate 3: Does the artificial pulse improve washout?

P Fang, J Du, A Boraschi, S Bozzi… - Frontiers in …, 2022 - frontiersin.org
While earlier studies reported no relevant effect of the HeartMate 3 (HM3) artificial pulse
(AP) on bulk pump washout, its effect on regions with prolonged residence times remains …

A two-phase flow approach for modeling blood stasis and estimating the thrombosis potential of a ventricular assist device

WF Dai, P Wu, GM Liu - The International Journal of Artificial …, 2021 - journals.sagepub.com
Thrombosis and its related events have become a major concern during the development
and optimization of ventricular assist devices (VADs, also called blood pumps), and limit …

Fluid–structure interaction modelling of a positive-displacement Total Artificial Heart

J Bornoff, A Najar, L Fresiello, T Finocchiaro… - Scientific reports, 2023 - nature.com
For those suffering from end-stage biventricular heart failure, and where a heart
transplantation is not a viable option, a Total Artificial Heart (TAH) can be used as a bridge to …

Experimental and numerical investigation of different geometrical parameters in a centrifugal blood pump

SE Hosseini, A Keshmiri - Research on Biomedical Engineering, 2022 - Springer
Purpose Due to the importance of public health and economics, cardiovascular disease has
become one of the most important debates and challenges for scientists. However, few …

[HTML][HTML] Blood trauma potential of the HeartWare Ventricular Assist Device in pediatric patients

M Granegger, B Thamsen, T Schlöglhofer… - The Journal of thoracic …, 2020 - Elsevier
Objective Mechanical circulatory support has become a standard therapy for adult patients
with end-stage heart failure. For pediatric patients, technologic development lags behind …

Extended finite element method for fluid‐structure interaction in wave membrane blood pump

M Martinolli, J Biasetti, S Zonca… - International Journal …, 2021 - Wiley Online Library
Numerical simulations of cardiac blood pump systems are integral to the optimization of
device design, hydraulic performance and hemocompatibility. In wave membrane blood …

Influence of turbulent shear stresses on the numerical blood damage prediction in a ventricular assist device

B Torner, L Konnigk, FH Wurm - The International journal of …, 2019 - journals.sagepub.com
The blood damage prediction in rotary blood pumps is an important procedure to evaluate
the hemocompatibility of such systems. Blood damage is caused by shear stresses to the …

Turbulence and turbulent flow structures in a ventricular assist device—a numerical study using the large‐eddy simulation

B Torner, L Konnigk, N Abroug… - International journal for …, 2021 - Wiley Online Library
Numerical flow simulations that analyze the turbulent flow characteristics within a turbopump
are important for optimizing the efficiency of such machines. In the case of ventricular assist …

Computational fluid–structure interaction study of a new wave membrane blood pump

M Martinolli, F Cornat, C Vergara - Cardiovascular Engineering and …, 2022 - Springer
Purpose Wave membrane blood pumps (WMBP) are novel pump designs in which blood is
propelled by means of wave propagation by an undulating membrane. In this paper, we …