Ketamine in neuropsychiatric disorders: an update

JN Johnston, B Kadriu, C Kraus, ID Henter… - …, 2024 - nature.com
The discovery of ketamine as a rapid-acting antidepressant led to a new era in the
development of neuropsychiatric therapeutics, one characterized by an antidepressant …

Efficacy and acceptability of cognitive‐behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive‐compulsive disorder: a network meta‐analysis

M Cervin, JF McGuire, JM D'Souza… - Journal of Child …, 2024 - Wiley Online Library
Background Cognitive‐behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs)
are recommended treatments for pediatric obsessive‐compulsive disorder (OCD), but their …

Rational and translational implications of D-amino acids for treatment-resistant schizophrenia: from neurobiology to the clinics

A de Bartolomeis, L Vellucci, MC Austin, G De Simone… - Biomolecules, 2022 - mdpi.com
Schizophrenia has been conceptualized as a neurodevelopmental disorder with synaptic
alterations and aberrant cortical–subcortical connections. Antipsychotics are the mainstay of …

Closing the gap for children with OCD: a staged-care model of cognitive behavioural therapy with exposure and response prevention

LJ Farrell, AM Waters, EA Storch, G Simcock… - Clinical Child and …, 2023 - Springer
Childhood obsessive–compulsive disorder (OCD) is among the most prevalent and
disabling mental health conditions affecting children and adolescents. Although the distress …

Do single‐case experimental designs lead to randomised controlled trials of cognitive behavioural therapy interventions for adolescent anxiety and related disorders …

T Cawthorne, A Käll, S Bennett, E Baker… - JCPP …, 2023 - Wiley Online Library
Abstract Background Although Cognitive Behavioural Therapy (CBT) is effective for 60% of
adolescents with anxiety disorders, only 36% are in remission post‐intervention. This …

FAST CBT for pediatric OCD: A multiple-baseline controlled pilot trial of parent training in exposure and response prevention delivered via telehealth

LJ Farrell, NA Nabinger de Diaz, S Mathieu… - Frontiers in …, 2022 - frontiersin.org
Objective The current study utilized a single case series, non-concurrent multiple baseline
design to examine the efficacy of training parents via telehealth videoconferencing in …

The effectiveness of exposure and response prevention combined with pharmacotherapy for obsessive-compulsive disorder: A systematic review and meta-analysis

L Mao, M Hu, L Luo, Y Wu, Z Lu, J Zou - Frontiers in psychiatry, 2022 - frontiersin.org
Objective To systematically evaluate the effectiveness of exposure and response prevention
(ERP) combined with medication on obsessive-compulsive disorder (OCD). Methods …

Exploring latent clusters in pediatric OCD based on symptoms, severity, age, gender, and comorbidity

O Smárason, RR Selles, DRMA Højgaard… - European Child & …, 2024 - Springer
Given diverse symptom expression and high rates of comorbid conditions, the present study
explored underlying commonalities among OCD-affected children and adolescents to better …

Pediatric Treatment-Resistant Obsessive Compulsive Disorder: Treatment Options and Challenges

S Younus, L Havel, JT Stiede, CE Rast, K Saxena… - Pediatric Drugs, 2024 - Springer
Pediatric obsessive-compulsive disorder (OCD) is a chronic, potentially debilitating
psychiatric condition. Although effective treatments exist, at least 10% of youth do not …

An overview of the pharmacological options for pediatric obsessive-compulsive disorder

D Marazziti, A Pozza - Expert Opinion on Pharmacotherapy, 2022 - Taylor & Francis
Introduction Childhood and adolescence represent critical stages for the development of
obsessive-compulsive disorder (OCD). According to recent guidelines and meta-analyses …