Controlled drug delivery systems: current status and future directions

S Adepu, S Ramakrishna - Molecules, 2021 - mdpi.com
The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

Flavonoid transport across blood-brain barrier: Implication for their direct neuroprotective actions

A Faria, N Mateus, C Calhau - Nutrition and Aging, 2012 - content.iospress.com
Epidemiological and dietary intervention studies in humans and animals indicate that
flavonoid consumption may be capable of promoting brain health. However, the knowledge …

Ligand-displaying-exosomes using RNA nanotechnology for targeted delivery of multi-specific drugs for liver cancer regression

S Ellipilli, H Wang, DW Binzel, D Shu, P Guo - … , Biology and Medicine, 2023 - Elsevier
Liver cancer such as hepatocellular carcinoma (HCC) poorly responds to
chemotherapeutics as there are no effective means to deliver the drugs to liver cancer. Here …

[HTML][HTML] Novel NIR-II fluorescent probes for biliary atresia imaging

X Zeng, Y Liao, X Qiao, K Liang, Q Luo, M Deng… - … Pharmaceutica Sinica B, 2023 - Elsevier
Biliary atresia is a rare infant disease that predisposes patients to liver transplantation and
death if not treated in time. However, early diagnosis is challenging because the clinical …

Phytochemical-Based Evidence of the Health Benefits of Bidens Pilosa Extracts and Cytotoxicity

OA Idris, N Kerebba, S Horn, MS Maboeta, R Pieters - Chemistry Africa, 2023 - Springer
Purpose Bidens pilosa L. is traditionally used as a flavouring agent in foods, in the treatment
of diseases, in agriculture as a biopesticide and herbicide, and in the phytoremediation of …

Considerations for setting occupational exposure limits for novel pharmaceutical modalities

JC Graham, J Hillegass, G Schulze - Regulatory Toxicology and …, 2020 - Elsevier
In order to develop new and effective medicines, pharmaceutical companies must be
modality agnostic. As science reveals an enhanced understanding of biological processes …

Understanding lymphatic drug delivery through chylomicron blockade: A retrospective and prospective analysis

M Yousef, N Bou-Chacra, R Löbenberg… - … of Pharmacological and …, 2024 - Elsevier
Scientists have developed and employed various models to investigate intestinal lymphatic
uptake. One approach involves using specific blocking agents to influence the chylomicron …

Physiological oxygen and co-culture with human fibroblasts facilitate in vivo-like properties in human renal proximal tubular epithelial cells

F Piossek, S Beneke, N Schlichenmaier… - Chemico-Biological …, 2022 - Elsevier
Reliable prediction of compound mediated nephrotoxicity in humans is still unsatisfactory
irrespective of the recent advancements in in silico, in vitro and in vivo models. Therefore …

Polycaprolactone-based Nanocarriers Containing 5-fluorouracil as a Therapeutic Guided Drug Delivery Approach for Enhancing Anticancer Activity

S Mohammadian, M Khazaei… - Current Cancer Drug …, 2023 - ingentaconnect.com
Nowadays, nano-platforms designed for drug delivery systems (DDSs) such as polymers,
liposomes, and micelles have been demonstrated to be clinically efficient. The sustained …

Stakeholders' perspectives about the impact of training and sensitization of traditional and spiritual healers on mental health and illness: A qualitative evaluation in …

PB Yaro, E Asampong, PTN Tabong… - … Journal of Social …, 2020 - journals.sagepub.com
Background: Prayer camps and traditional healers have emerged recently as alternative
sources of mental health care in Ghana. To increase their knowledge and collaboration …