The Ten-eleven translocation (TET) family of dioxygenases mediate cytosine demethylation
by catalyzing the oxidation of 5-methylcytosine (5mC). TET-mediated DNA demethylation …

Cleidocranial dysplasia (CCD) spectrum disorder is a skeletal dysplasia that represents a
clinical continuum ranging from classic CCD (triad of delayed closure of the cranial sutures …

Introduction Cleidocranial dysplasia (CCD) is a rare disease characterized by craniofacial,
skeletal, and oral anomalies. The disease prevalence is estimated to be 1 per million …

Syringic acid (SA), a phenolic acid, has been used in Chinese and Indian medicine for
treating diabetes but its role in osteogenesis has not yet been investigated. In the present …

Cleidocranial dysplasia is an autosomal dominant skeletal disorder resulting from RUNX2
mutations. The influence of RUNX2 mutations on osteoclastogenesis and bone resorption …

Cleidocranial dysplasia (CCD) is an autosomal dominant inheritable skeletal disorder
characterized by cranial dysplasia, clavicle hypoplasia and dental abnormalities. This …

Craniosynostosis refers to a condition during early development in which one or more of the
fibrous sutures of the skull prematurely fuse by turning into bone, which produces …

Cleidocranial Dysplasia (CCD) is a rare genetic disorder characterized by skeletal
abnormalities and dental anomalies, primarily caused by variants in the RUNX2 gene …

Cleidocranial dysplasia (CCD) is a rare autosomal dominant skeletal dysplasia caused by
runt-related transcription factor 2 (RUNX2) mutations. In addition to the regular missense …

Loss or decrease of function in runt‐related transcription factor 2 encoded by RUNX2 is
known to cause a rare autosomal‐dominant skeletal disorder, cleidocranial dysplasia …