Nitric oxide, nitric oxide derivatives and reactive oxygen intermediates are toxic molecules of
the immune system which contribute to the control of microbial pathogens and tumors. There …

The metabolite glutathione fulfills many important and chemically complex roles in protecting
cellular components from the deleterious effects of toxic species. GSH combines with …

Entamoeba histolytica is a protozoan parasite and the causative agent of amebiasis. It is
estimated approximately 1% of humans are infected with E. histolytica, resulting in an …

The “amitochondriate” protozoan parasites of humans Entamoeba histolytica, Giardia
intestinalis, and Trichomonas vaginalis share many biochemical features, eg, energy and …

The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft
genome sequence has been published. Although the genome is still incomplete, it is …

Vaccination of BALB/c mice with Leishmania major promastigote culture filtrate proteins plus
Corynebacterium parvum confers resistance to infection with L. major. To define …

Thiol-dependent hydroperoxide metabolism in parasites is reviewed in respect to potential
therapeutic strategies. The hydroperoxide metabolism of Crithidia fasciculata has been …

The protozoan parasite, Giardia duodenalis, shares many metabolic and genetic attributes
of the bacteria, including fermentative energy metabolism which relies heavily on …

Leishmaniasis is an endemic tropical disease in South America, with few therapeutic
approaches. Snake venoms are complex protein mixtures with biological actions that could …

Trypanosoma cruziglutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid,
phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which …