Catheter-associated urinary tract infections: current challenges and future prospects

GT Werneburg - Research and reports in urology, 2022 - Taylor & Francis
Catheter-associated urinary tract infection (CAUTI) is the most common healthcare-
associated infection and cause of secondary bloodstream infections. Despite many …

Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies

RD Klein, SJ Hultgren - Nature Reviews Microbiology, 2020 - nature.com
Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-
threatening. The continued emergence of antibiotic resistance, together with our increasing …

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

SW Dickey, GYC Cheung, M Otto - Nature Reviews Drug Discovery, 2017 - nature.com
The rapid evolution and dissemination of antibiotic resistance among bacterial pathogens
are outpacing the development of new antibiotics, but antivirulence agents provide an …

Biofilm-associated infection by enterococci

JH Ch'ng, KKL Chong, LN Lam, JJ Wong… - Nature Reviews …, 2019 - nature.com
Enterococci are ubiquitous members of the human gut microbiota and frequent causes of
biofilm-associated opportunistic infections. Enterococci cause 25% of all catheter-associated …

Pathophysiology, treatment, and prevention of catheter-associated urinary tract infection

A Flores-Mireles, TN Hreha… - Topics in spinal cord …, 2019 - meridian.allenpress.com
Urinary tract infections (UTIs) are among the most common microbial infections in humans
and represent a substantial burden on the health care system. UTIs can be uncomplicated …

The emerging problem of linezolid-resistant enterococci

R Bi, T Qin, W Fan, P Ma, B Gu - Journal of global antimicrobial resistance, 2018 - Elsevier
Enterococcus is a significant pathogen in numerous infections, particularly in nosocomial
infections, and is thus a great challenge to clinicians. Linezolid (LNZ), an oxazolidinone …

Inhibiting host-protein deposition on urinary catheters reduces associated urinary tract infections

MJ Andersen, CK Fong, AA La Bella, JJ Molina… - Elife, 2022 - elifesciences.org
Microbial adhesion to medical devices is common for hospital-acquired infections,
particularly for urinary catheters. If not properly treated these infections cause complications …

Reaching the end of the line: urinary tract infections

KO Tamadonfar, NS Omattage… - Microbiology …, 2019 - Am Soc Microbiol
Urinary tract infections (UTIs) cause a substantial health care burden. UTIs (i) are most often
caused by uropathogenic Escherichia coli (UPEC),(ii) primarily affect otherwise healthy …

Urinary catheter coating modifications: the race against catheter-associated infections

MJ Andersen, AL Flores-Mireles - Coatings, 2019 - mdpi.com
Urinary catheters are common medical devices, whose main function is to drain the bladder.
Although they improve patients' quality of life, catheter placement predisposes the patient to …

Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract

JN Walker, AL Flores-Mireles… - Proceedings of the …, 2017 - National Acad Sciences
Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging cause of catheter-
associated urinary tract infection (CAUTI), which frequently progresses to more serious …