Ciprofloxacin is a broad spectrum fluoroquinolone antibacterial agent. Since its introduction
in the 1980s, most Gram-negative bacteria have remained highly susceptible to this agent in …

Importance The optimal duration of antibiotic treatment for community-acquired pneumonia
(CAP) has not been well established. Objective To validate Infectious Diseases Society of …

Chronic infections are associated with exacerbation in patients with chronic obstructive
pulmonary disease (COPD). The major objective of the management of these patients is the …

Context The novel influenza A (H1N1) pandemic affected Australia and New Zealand during
the 2009 southern hemisphere winter. It caused an epidemic of critical illness and some …

Rationale: Some studies have shown a beneficial effect of corticosteroids in patients with
community-acquired pneumonia (CAP), possibly by diminishing local and systemic …

Objective Pseudomonas aeruginosa is a frequent cause of ventilator-associated
pneumonia. Recent evidence suggests that production of type III secretion proteins is …

Objective To compare the effectiveness of discontinuing treatment with amoxicillin after three
days or eight days in adults admitted to hospital with mild to moderate-severe community …

The use of microbiologic investigations in routine clinical practice, their value in guiding
antibiotic prescription, and their influence on outcome were prospectively studied in 113 …

We conducted a prospective, open-label study to delineate a relationship between exposure
and outcomes in 36 patients treated with cefepime. Twenty patients had documented Gram …

Intravenously administered ciprofloxacin was compared with imipenem for the treatment of
severe pneumonia. In this prospective, randomized, double-blind, multicenter trial, which …