Volume visualization: a technical overview with a focus on medical applications

Q Zhang, R Eagleson, TM Peters - Journal of digital imaging, 2011 - Springer
With the increasing availability of high-resolution isotropic three-or four-dimensional medical
datasets from sources such as magnetic resonance imaging, computed tomography, and …

Precise cerebral vascular atlas in stereotaxic coordinates of whole mouse brain

B Xiong, A Li, Y Lou, S Chen, B Long, J Peng… - Frontiers in …, 2017 - frontiersin.org
Understanding amazingly complex brain functions and pathologies requires a complete
cerebral vascular atlas in stereotaxic coordinates. Making a precise atlas for cerebral …

Characterization of biological processes through automated image analysis

J Rittscher - Annual Review of Biomedical Engineering, 2010 - annualreviews.org
The systems-level analysis of complex biological processes requires methods that enable
the quantification of a broad range of phenotypical alterations, the precise localization of …

3D BrainCV: simultaneous visualization and analysis of cells and capillaries in a whole mouse brain with one-micron voxel resolution

J Wu, Y He, Z Yang, C Guo, Q Luo, W Zhou, S Chen… - Neuroimage, 2014 - Elsevier
Systematic cellular and vascular configurations are essential for understanding fundamental
brain anatomy and metabolism. We demonstrated a 3D brainwide cellular and vascular …

Scalable and interactive segmentation and visualization of neural processes in EM datasets

WK Jeong, J Beyer, M Hadwiger… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Recent advances in scanning technology provide high resolution EM (Electron Microscopy)
datasets that allow neuro-scientists to reconstruct complex neural connections in a nervous …

NetMets: software for quantifying and visualizing errors in biological network segmentation

D Mayerich, C Bjornsson, J Taylor, B Roysam - BMC bioinformatics, 2012 - Springer
One of the major goals in biomedical image processing is accurate segmentation of
networks embedded in volumetric data sets. Biological networks are composed of a …

Multiscale exploration of mouse brain microstructures using the knife-edge scanning microscope brain atlas

JR Chung, C Sung, D Mayerich, J Kwon… - Frontiers in …, 2011 - frontiersin.org
Connectomics is the study of the full connection matrix of the brain. Recent advances in high-
throughput, high-resolution 3D microscopy methods have enabled the imaging of whole …

Robust tracing and visualization of heterogeneous microvascular networks

PA Govyadinov, T Womack, JL Eriksen… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Advances in high-throughput imaging allow researchers to collect three-dimensional images
of whole organ microvascular networks. These extremely large images contain networks that …

Knife-edge scanning microscopy for connectomics research

Y Choe, D Mayerich, J Kwon, DE Miller… - … Joint Conference on …, 2011 - ieeexplore.ieee.org
In this paper, we will review a novel microscopy modality called Knife-Edge Scanning
Microscopy (KESM) that we have developed over the past twelve years (since 1999) and …

Graph-assisted visualization of microvascular networks

P Govyadinov, T Womack, J Eriksen… - 2019 IEEE …, 2019 - ieeexplore.ieee.org
Microvessels are frequent targets for research into tissue development and disease
progression. These complex and subtle differences between networks are currently difficult …