Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …

Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

Background Multifunctional stimuli-responsive nanoparticles with photothermal-
chemotherapy provided a powerful tool for improving the accuracy and efficiency in the …

Prostate cancer (PC) is the second most common cause of death amongst men in the USA.
Therapy of PC has been transformed in the past decade by introducing novel therapeutics …

Prostate cancer (PC) is the most prevalent male urogenital cancer worldwide. PC patients
presenting an advanced or metastatic cancer succumb to the disease, even after therapeutic …

Peptides are signaling epitopes that control many vital biological events. Increased
specificity, synthetic feasibility with concomitant lack of toxicity, and immunogenicity make …

Cancer, one of the lethal threats to human health, is most frequently treated with surgery,
chemotherapy and radiation. Specific receptors and abnormal physiochemical conditions …

Proteases have a fundamental role in maintaining physiological homeostasis, but their
dysregulation results in severe activity imbalance and pathological conditions, including …

Herein, we designed and synthesized novel reactive oxygen species (ROS)-responsive
glycol chitosan-doxorubicin (DOX) prodrug via a ROS-cleavable thioketal (TK) linker. The …

To achieve a fine balance between the onset of therapeutic efficacy and the incidence of
side effects, various drug delivery systems have been intelligently fabricated to achieve …