Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

One of the most neglected aspects of chemotherapy are changes, and possible
consequences of these changes, that occur in normal somatic cells. In this review, we …

Cancer is a relevant public health problem that represents the second leading cause of
global death. In this regard, cisplatin is a highly effective antineoplastic drug used in …

Despite the enormous advances made in the field of oncology, no solution to the side effect
of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 …

Cisplatin (CP), an effective chemotherapeutic drug, has been widely used to treat the
several types of tumors. Orientin (ORI) is a flavonoid that shows versatile therapeutic …

Background Cisplatin-based chemotherapy may induce nephrotoxicity. This study presents
a random forest predictive model that identifies testicular cancer patients at risk of …

Nephrotoxicity of cisplatin (CP) involves renal oxidative stress and inflammation, and
sesamin (a major liganin in many plants) has strong antioxidant and antiinflammatory …

Cisplatin is a platinum-based cytostatic drug that is widely used for cancer treatment.
Mitochondria and mtDNA are important targets for platinum-based cytostatics, which …

Radiotherapy can be employed as a therapeutic modality alone in the early stages of cancer
and is used together with other treatments such as surgery and chemotherapy in more …

Objective Our previous research has shown that the expression of S100 calcium-binding
protein A9 (S100A9) in tumor cells was associated with neoadjuvant chemotherapy …